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Gene

usp33

ID
ZDB-GENE-040426-2323
Name
ubiquitin specific peptidase 33
Symbol
usp33 Nomenclature History
Previous Names
  • zgc:77308 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable cysteine-type endopeptidase activity; thiol-dependent deubiquitinase; and zinc ion binding activity. Predicted to be involved in several processes, including axon guidance; centrosome duplication; and protein deubiquitination. Predicted to act upstream of or within endocytosis and ubiquitin-dependent protein catabolic process. Predicted to be located in centrosome. Predicted to be active in cytoplasm. Orthologous to human USP33 (ubiquitin specific peptidase 33).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Tse et al., 2009
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With usp33 Human Ortholog
No data available
Associated With usp33 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018200 Ubiquitin specific protease, conserved site
Domain IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase
Domain IPR001607 Zinc finger, UBP-type
Domain IPR006615 Peptidase C19, ubiquitin-specific peptidase, DUSP domain
Domain IPR028889 Ubiquitin specific protease domain
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR035927 DUSP-like superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length DUSP-like superfamily Papain-like cysteine peptidase superfamily Peptidase C19, ubiquitin carboxyl-terminal hydrolase Peptidase C19, ubiquitin-specific peptidase, DUSP domain Ubiquitin specific protease, conserved site Ubiquitin specific protease domain Zinc finger, RING/FYVE/PHD-type Zinc finger, UBP-type
UniProtKB:A5PMR4 59
UniProtKB:A5PMR2 897
UniProtKB:A5PMR3 77
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations