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ZIRC
ZFIN ID: ZDB-GENE-040426-2281
Gene Name: liver-enriched gene 1, tandem duplicate 2
Gene Symbol: leg1.2    Nomenclature History

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Attributions

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Previous Names: leg1b (1), zgc:77778 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Involved in digestive system development and liver development. Localizes to the extracellular space. Is expressed in liver and yolk syncytial layer. Orthologous to human C6orf58 (chromosome 6 open reading frame 58).
Genome Resources: Alliance (1),  Gene:406484 (1),  Ensembl(GRCz11):ENSDARG00000095751 (2)
GENE EXPRESSION
All Expression Data: 10 figures from 3 publications
Directly Submitted Expression Data: 7 figures (7 images) from Thisse et al., 2004 [MGC:77778]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1814 Point Mutation Unknown Missense ENU
sa6612 Point Mutation Unknown Premature Stop ENU
sa10898 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-leg1.1,leg1.2 N/A 2
    MO1-leg1.2 N/A 1
    PHENOTYPE
    Data: Fig. 5 from Chang et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH leg1.2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH leg1.2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process digestive system development (more)
    Cellular Component extracellular space (more)
    Molecular Function molecular_function (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR008499 (1)
  • Pfam:PF05612 (1)
  • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA leg1.2-201 (1)    Ensembl 1383
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM leg1.2 No data available
    MARKER RELATIONSHIPS
    leg1.2 Contained in: [BAC] CH211-205N18 (1) (order this)
    leg1.2 Encodes: [cDNA] MGC:77778 (1) (order this), MGC:113937 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213203 (1) 1242 bp
    Genomic GenBank:AL954182 (1) 152215 bp
    Select Tool
    Polypeptide UniProtKB:A5PF59 (1) 364 aa
    Sequence Clusters UniGene:162096 (1)
    Sequence Information (all 14)
    ORTHOLOGY for leg1.2 ( Chr: 20 )
    CITATIONS (21)