Gene

amfra

ID
ZDB-GENE-040426-2190
Name
autocrine motility factor receptor a
Symbol
amfra Nomenclature History
Previous Names
  • amfr
  • wu:fi06e06
  • wu:fi37e05
  • zgc:63893 (1)
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Exhibits ubiquitin protein ligase activity. Involved in protein polyubiquitination and response to endoplasmic reticulum stress. Localizes to endoplasmic reticulum. Is expressed in brain; digestive system; eye; heart; and muscle. Orthologous to human AMFR (autocrine motility factor receptor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Chen et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With amfra Human Ortholog
No data available
Associated With amfra Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Domain IPR003892 Ubiquitin system component CUE
Domain IPR040675 E3 ubiquitin-protein ligase AMFR, Ube2g2-binding region
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length E3 ubiquitin-protein ligase AMFR, Ube2g2-binding region Ubiquitin system component CUE Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type
UniProtKB:Q6PFU8 620
UniProtKB:F1QB30 620
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-amfr monoclonal
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations