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ZIRC
ZFIN ID: ZDB-GENE-040426-2173
Gene Name: pyruvate dehydrogenase E1 beta subunit
Gene Symbol: pdhb
Sequence Ontology ID : SO:0000704

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Previous Names: nir (1), noir (1), wu:fc76a05, zgc:64062 (1)

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(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits pyruvate dehydrogenase activity. Involved in pigmentation. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human PDHB (pyruvate dehydrogenase  ...
GENE EXPRESSION
All Expression Data: 6 figures from 2 publications
Directly Submitted Expression Data: 4 figures (6 images) from Thisse et al., 2004 [MGC:64062]
  1 figure (1 image) from Thisse et al., 2004 [IMAGE:6895600]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa3153 Point Mutation Unknown Premature Stop ENU
sa12405 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tc22 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • tp89 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • DISEASE ASSOCIATED WITH pdhb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    pyruvate decarboxylase deficiency Pyruvate dehydrogenase E1-beta deficiency 614111
    DISEASE ASSOCIATED WITH pdhb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process pigmentation (more)
    Molecular Function pyruvate dehydrogenase activity (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pdhb-201 (1) 1421
    pdhb-202 (1) 880
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pdhb No data available
    MARKER RELATIONSHIPS
    pdhbContained in: [BAC] DKEYP-87E7 (1)
    pdhbEncodes: [EST] fc76a05 (1), IMAGE:6895600 (1) (order this)
    [cDNA] MGC:64062 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213154 (1) 1429bp
    Genomic GenBank:BX649457 (1) 159207bp
    Select Tool
    Polypeptide UniProtKB:Q7T368 (1) 359aa
    Sequence Clusters UniGene:3570 (1)
    Sequence Information (all 14)
    ORTHOLOGY for pdhb (Chr: 22)
    CITATIONS (35)