Gene

mhc1zba

ID
ZDB-GENE-040426-2149
Name
major histocompatibility complex class I ZBA
Symbol
mhc1zba Nomenclature History
Previous Names
  • zgc:64115 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to be involved in immune response. Predicted to localize to external side of plasma membrane and extracellular space. Is expressed in gill; intestine; kidney; liver; and spleen. Human ortholog(s) of this gene implicated in several diseases, including acute porphyria (multiple); arthritis (multiple); bone marrow cancer (multiple); hemochromatosis (multiple); and liver disease (multiple). Orthologous to several human genes including AZGP1 (alpha-2-glycoprotein 1, zinc-binding); HFE (homeostatic iron regulator); and HLA-E (major histocompatibility complex, class I, E).
Genome Resources
Note
None
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mhc1zba Human Ortholog
No data available
Associated With mhc1zba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
Domain IPR001039 MHC class I alpha chain, alpha1 alpha2 domains
Domain IPR003597 Immunoglobulin C1-set
Domain IPR007110 Immunoglobulin-like domain
Domain IPR011161 MHC class I-like antigen recognition-like
Homologous_superfamily IPR011162 MHC classes I/II-like antigen recognition protein
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Homologous_superfamily IPR037055 MHC class I-like antigen recognition-like superfamily
Domain Details Per Protein
Protein Length Immunoglobulin C1-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin/major histocompatibility complex, conserved site MHC classes I/II-like antigen recognition protein MHC class I alpha chain, alpha1 alpha2 domains MHC class I-like antigen recognition-like MHC class I-like antigen recognition-like superfamily
UniProtKB:A8E7F4 398
UniProtKB:A0A0N4STQ1 308
UniProtKB:Q7T345 387
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations