ZFIN ID: ZDB-GENE-040426-2146
Gene Name: MARCKS-like 1a
Gene Symbol: marcksl1a
Sequence Ontology ID : SO:0000704

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Previous Names: cb575 (1), marcksl1, marcksl1b (1), MLP (1), sb:cb575, wu:fa66h03, wu:fj18a04, zgc:65840

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
Note: Prieto and Zolessi (2017) suggest that the "a" and "b" designations, established in 2012, of the marcksl1 paralogs, should be reversed based on structural and functional similarities to the MARCKSL1 genes. No changes were made because the "a" and "b" designations are not reflective of priority in discovery, function or structure but are designated based on the evidence available at the time of the nomenclature event for the evolutionary and syntenic relationship to the ancestral gene.
AUTOMATED DESCRIPTION
Predicted to have calmodulin binding activity; involved in cartilage development, central nervous system development, and neural retina development; orthologous to human MARCKSL1 (MARCKS like 1).
GENE EXPRESSION
All Expression Data: 8 figures from 3 publications
Directly Submitted Expression Data: 6 figures (24 images) from Thisse et al., 2001 [cb575]
Wild-type Stages, Structures: Blastula:128-cell (2.25h-2.5h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE
Data: 4 figures from Prieto et al., 2017
Observed in:
DISEASE ASSOCIATED WITH marcksl1a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH marcksl1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cartilage development (more)
Cellular Component cytoplasm (more)
Molecular Function calmodulin binding (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002101 (1)
  • PROSITE:PS00826 (1)
  • Pfam:PF02063 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA marcksl1a-201 (1) 1694
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM marcksl1a No data available
    MARKER RELATIONSHIPS
    marcksl1aContained in: [Fosmid] CH1073-139I9 (1) (order this)
    marcksl1aContains: [STS] chunp30001, chunp30369
    marcksl1aEncodes: [EST] cb575 (1) (order this), fa66h03 (1), fj18a04 (1)
    [cDNA] MGC:65840 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213133 (1) 1690bp
    Genomic GenBank:CU571066 (1) 32034bp
    Select Tool
    Polypeptide UniProtKB:Q6PD99 (1) 213aa
    Sequence Clusters UniGene:75946 (1)
    Sequence Information (all 18)
    OTHER marcksl1a GENE PAGES
  • Alliance (1)
  • Gene:406407 (1)
  • VEGA:OTTDARG00000029502 (1)
  • Ensembl(GRCz11):ENSDARG00000039034 (2)
  • ORTHOLOGY for marcksl1a (Chr: 13)
    CITATIONS (22)