Gene

elmo1

ID
ZDB-GENE-040426-2069
Name
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
Symbol
elmo1 Nomenclature History
Previous Names
  • im:7151147
  • wu:fq24e08
  • zgc:85612 (1)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have SH3 domain binding activity. Involved in cilium assembly; lymphangiogenesis; and positive regulation of angiogenesis. Predicted to localize to guanyl-nucleotide exchange factor complex and plasma membrane. Is expressed in several structures, including blood vessel; immature eye; mesoderm; nervous system; and pronephric tubule. Orthologous to human ELMO1 (engulfment and cell motility 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
26 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With elmo1 Human Ortholog
No data available
Associated With elmo1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001849 Pleckstrin homology domain
Domain IPR006816 ELMO domain
Domain IPR024574 Domain of unknown function DUF3361
Family IPR030715 Engulfment and cell motility protein 1
Homologous_superfamily IPR011989 Armadillo-like helical
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Domain Details Per Protein
Protein Length Armadillo-like helical Armadillo-type fold Domain of unknown function DUF3361 ELMO domain Engulfment and cell motility protein 1 PH-like domain superfamily Pleckstrin homology domain
UniProtKB:A0A0R4IHP8 740
UniProtKB:A0A0R4IJC9 243
UniProtKB:A0A2R8RS12 728
UniProtKB:Q6NV39 726
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-elmo1 polyclonal Goat
  • WB
Everest Biotech
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations