Gene

grb2b

ID
ZDB-GENE-040426-1975
Name
growth factor receptor-bound protein 2b
Symbol
grb2b Nomenclature History
Previous Names
  • grb2
  • fb18e12
  • wu:fb18e12
  • wu:fb34e06
  • zgc:73077
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Human ortholog(s) of this gene implicated in breast cancer; prostate adenocarcinoma; and prostate cancer. Is expressed in central nervous system and trigeminal placode. Orthologous to human GRB2 (growth factor receptor bound protein 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grb2b Human Ortholog
No data available
Associated With grb2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000980 SH2 domain
Domain IPR001452 SH3 domain
Domain IPR035641 GRB2, N-terminal SH3 domain
Domain IPR035643 GRB2, C-terminal SH3 domain
Homologous_superfamily IPR036028 SH3-like domain superfamily
Homologous_superfamily IPR036860 SH2 domain superfamily
Domain Details Per Protein
Protein Length GRB2, C-terminal SH3 domain GRB2, N-terminal SH3 domain SH2 domain SH2 domain superfamily SH3 domain SH3-like domain superfamily
UniProtKB:E9QFV9 149
UniProtKB:Q6PC73 217
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations