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Gene

ppib

ID
ZDB-GENE-040426-1955
Name
peptidylprolyl isomerase B (cyclophilin B)
Symbol
ppib Nomenclature History
Previous Names
  • cb87 (1)
  • sb:cb87
  • wu:fa97f08
  • zgc:73214 (1)
  • zgc:86796
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding and protein peptidyl-prolyl isomerization. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in several structures, including axis; hatching gland; notochord; pectoral fin musculature; and polster. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Orthologous to human PPIB (peptidylprolyl isomerase B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppib Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
osteogenesis imperfecta type 9 Alliance Osteogenesis imperfecta, type IX 259440
Associated With ppib Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
Domain IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
Family IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase
Homologous_superfamily IPR029000 Cyclophilin-like domain superfamily
Domain Details Per Protein
Protein Length Cyclophilin-like domain superfamily Cyclophilin-type peptidyl-prolyl cis-trans isomerase Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
UniProtKB:F6NLI6 208
UniProtKB:Q6PBW4 216
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations