Gene

rdh8b

ID
ZDB-GENE-040426-1759
Name
retinol dehydrogenase 8b
Symbol
rdh8b Nomenclature History
Previous Names
  • rdh8l
  • zf 1.3 (1)
  • zfprRDH1 (1)
  • zgc:73320
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable NADP-retinol dehydrogenase activity and estradiol 17-beta-dehydrogenase activity. Predicted to act upstream of or within estrogen biosynthetic process. Predicted to be located in cytoplasm and membrane. Is expressed in brain; eye; fin; retina; and retinal photoreceptor layer. Orthologous to human RDH8 (retinol dehydrogenase 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rdh8b Human Ortholog
No data available
Associated With rdh8b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020904 Short-chain dehydrogenase/reductase, conserved site
Family IPR002347 Short-chain dehydrogenase/reductase SDR
Family IPR011348 17beta-dehydrogenase
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length 17beta-dehydrogenase NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase, conserved site Short-chain dehydrogenase/reductase SDR
UniProtKB:F1QT23 317
UniProtKB:Q7T2I9 317
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations