Gene

chchd10

ID
ZDB-GENE-040426-1753
Name
coiled-coil-helix-coiled-coil-helix domain containing 10
Symbol
chchd10 Nomenclature History
Previous Names
  • chchd2
  • zgc:73308
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Acts upstream of or within axonogenesis and skeletal myofibril assembly. Predicted to be active in mitochondrion and nucleus. Is expressed in several structures, including adaxial cell; digestive system; musculature system; nervous system; and trunk. Used to study motor neuron disease. Human ortholog(s) of this gene implicated in frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Orthologous to human CHCHD10 (coiled-coil-helix-coiled-coil-helix domain containing 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Brockmann et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chchd10 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
frontotemporal dementia and/or amyotrophic lateral sclerosis-2 Alliance Frontotemporal dementia and/or amyotrophic lateral sclerosis 2 615911
Spinal muscular atrophy, Jokela type 615048
?Myopathy, isolated mitochondrial, autosomal dominant 616209
Associated With chchd10 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations