Gene

timm50

ID
ZDB-GENE-040426-1618
Name
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
Symbol
timm50 Nomenclature History
Previous Names
  • zgc:66357 (1)
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Acts upstream of or within apoptotic process. Predicted to be located in mitochondrial inner membrane. Predicted to be part of TIM23 mitochondrial import inner membrane translocase complex. Is expressed in several structures, including immature eye; margin; midbrain; pectoral fin musculature; and segmental plate. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 9. Orthologous to human TIMM50 (translocase of inner mitochondrial membrane 50).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With timm50 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
3-methylglutaconic aciduria type 9 Alliance 3-methylglutaconic aciduria, type IX 617698
Associated With timm50 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004274 FCP1 homology domain
Family IPR027111 Mitochondrial import inner membrane translocase subunit Tim50
Homologous_superfamily IPR023214 HAD superfamily
Homologous_superfamily IPR036412 HAD-like superfamily
Domain Details Per Protein
Protein Length FCP1 homology domain HAD-like superfamily HAD superfamily Mitochondrial import inner membrane translocase subunit Tim50
UniProtKB:B2GQE9 387
UniProtKB:F1QCT0 387
UniProtKB:A0A2R8Q8J6 381
UniProtKB:Q6NWD4 387
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations