ZFIN ID: ZDB-GENE-040426-1614
Gene Name: cell adhesion molecule 2a
Gene Symbol: cadm2a    Nomenclature History

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Previous Names: igsf4d (1), zgc:66339 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 10 Mapping Details/Browsers
Description: Predicted to localize to the integral component of membrane. Is expressed in immature eye; nervous system; and pancreatic system. Orthologous to human CADM2 (cell adhesion molecule 2).
Genome Resources: Alliance (1),  Gene:793954 (1),  Ensembl(GRCz11):ENSDARG00000009930 (1)
GENE EXPRESSION
All Expression Data: 12 figures from 3 publications
Directly Submitted Expression Data: 4 figures (7 images) from Thisse et al., 2004 [MGC:66339]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa4371 Point Mutation Unknown Splice Site ENU
sa21731 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34900 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-cadm2a
    1
    CRISPR2-cadm2a
    1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cadm2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cadm2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Cellular Component integral component of membrane (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
    Domain IPR003585 Neurexin/syndecan/glycophorin C
    Domain IPR003598 Immunoglobulin subtype 2
    Domain IPR003599 Immunoglobulin subtype
    Domain IPR007110 Immunoglobulin-like domain
    Domain IPR013098 Immunoglobulin I-set
    Domain IPR013106 Immunoglobulin V-set domain
    Domain IPR013162 CD80-like, immunoglobulin C2-set
    Homologous_superfamily IPR013783 Immunoglobulin-like fold
    Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cadm2a-202 (1)    Ensembl 994
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-cadm2a polyclonal Rabbit IHC 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cadm2a No data available
    MARKER RELATIONSHIPS
    cadm2a Contained in: [BAC] DKEYP-100G5 (1)
    cadm2a Encodes: [cDNA] cssl:d218 (1), MGC:66339 (1), MGC:173997 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200664 (1) 2256 nt
    Genomic GenBank:CR925745 (1) 197787 nt
    Select Tool
    Polypeptide UniProtKB:Q6PFK4 (1) 405 aa
    Sequence Information (all 32)
    ORTHOLOGY for cadm2a ( Chr: 10 )
    CITATIONS (26)