ZFIN ID: ZDB-GENE-040426-1492
Gene Name: adenine phosphoribosyltransferase
Gene Symbol: aprt    Nomenclature History

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Previous Name: zgc:65965

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have AMP binding activity; adenine binding activity; and adenine phosphoribosyltransferase activity. Predicted to be involved in AMP salvage and adenine salvage. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in adenine phosphoribosyltransferase deficiency. Orthologous to human APRT (adenine phosphoribosyltransferase).
Genome Resources: Alliance (1),  Gene:393641 (1),  Ensembl(GRCz11):ENSDARG00000003519 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la026165Tg Transgenic Insertion Unknown Unknown DNA
sa12964 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH aprt HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    adenine phosphoribosyltransferase deficiency Alliance Adenine phosphoribosyltransferase deficiency 614723
    DISEASE ASSOCIATED WITH aprt VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process adenine salvage (more)
    Cellular Component cytoplasm (more)
    Molecular Function adenine phosphoribosyltransferase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA aprt-201 (1)    Ensembl 473
    aprt-202 (1)    Ensembl 2741
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM aprt No data available
    MARKER RELATIONSHIPS
    aprt Contained in: [BAC] CH211-196P1 (1)
    aprt Encodes: [cDNA] MGC:65965 (1), MGC:174807 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200668 (1) 2729 nt
    Genomic GenBank:CR376726 (1) 155854 nt
    Select Tool
    Polypeptide UniProtKB:A9JRT0 (1) 177 aa
    Sequence Information (all 14)
    ORTHOLOGY for aprt ( Chr: 7 )
    CITATIONS (25)