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Gene

aprt

ID
ZDB-GENE-040426-1492
Name
adenine phosphoribosyltransferase
Symbol
aprt Nomenclature History
Previous Names
  • zgc:65965
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to enable AMP binding activity; adenine binding activity; and adenine phosphoribosyltransferase activity. Predicted to be involved in AMP salvage and adenine salvage. Predicted to act upstream of or within purine ribonucleoside salvage. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in adenine phosphoribosyltransferase deficiency. Orthologous to human APRT (adenine phosphoribosyltransferase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aprt Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
adenine phosphoribosyltransferase deficiency Alliance Adenine phosphoribosyltransferase deficiency 614723
Associated With aprt Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000836 Phosphoribosyltransferase domain
Family IPR005764 Adenine phosphoribosyl transferase
Homologous_superfamily IPR029057 Phosphoribosyltransferase-like
Domain Details Per Protein
Protein Length Adenine phosphoribosyl transferase Phosphoribosyltransferase domain Phosphoribosyltransferase-like
UniProtKB:Q6PEI8 177
UniProtKB:F1QAP2 118
UniProtKB:F8W4R3 177
UniProtKB:A9JRT0 177
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations