ZFIN ID: ZDB-GENE-040426-1474
Gene Name: charged multivesicular body protein 1A
Gene Symbol: chmp1a    Nomenclature History

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Previous Names: pcoln3, wu:fb50a12, zgc:65914, zgc:85863

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Involved in cerebellum development. Predicted to localize to ESCRT III complex and multivesicular body. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 8. Orthologous to human CHMP1A (charged multivesicular body protein 1A).
Genome Resources: Alliance (1),  Gene:393535 (1),  Ensembl(GRCz11):ENSDARG00000102643 (1)
GENE EXPRESSION
All Expression Data: Fig. S3 from Mochida et al., 2012
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023361Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44367 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-chmp1a N/A 2
    MO2-chmp1a N/A 1
    DISEASE ASSOCIATED WITH chmp1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    pontocerebellar hypoplasia type 8 Alliance Pontocerebellar hypoplasia, type 8 614961
    DISEASE ASSOCIATED WITH chmp1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cerebellum development (more)
    Cellular Component cytoplasm (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chmp1a-203 (1)    Ensembl 1172
    ncRNA chmp1a-002 (1) 552
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-chmp1a polyclonal IgG Rabbit WB Abcam plc
    2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chmp1a No data available
    MARKER RELATIONSHIPS
    chmp1a Contained in: [Fosmid] CH1073-288B16 (1)
    chmp1a Encodes: [EST] fb50a12 (1)
    [cDNA] MGC:65914 (1), MGC:85863 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200563 (1) 1569 nt
    Genomic GenBank:CU633770 (1) 35489 nt
    Select Tool
    Polypeptide UniProtKB:A0A0R4IZC4 (1) 198 aa
    Sequence Information (all 22)
    ORTHOLOGY for chmp1a ( Chr: 25 )
    CITATIONS (27)