Gene

bhlhe22

ID
ZDB-GENE-040426-1411
Name
basic helix-loop-helix family, member e22
Symbol
bhlhe22 Nomenclature History
Previous Names
  • bhlhb5
  • Beta3.1 (1)
  • Beta3a (1)
  • wu:fq25e11
  • zgc:64225
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within neurogenesis and regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in immature eye; midbrain neural rod; nervous system; neural plate; and neural tube. Orthologous to human BHLHE22 (basic helix-loop-helix family member e22).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
22 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bhlhe22 Human Ortholog
No data available
Associated With bhlhe22 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR032654 Class E basic helix-loop-helix protein 22
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Class E basic helix-loop-helix protein 22 Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain
UniProtKB:F1R9F5 261
UniProtKB:Q5SEJ2 107
UniProtKB:Q7T301 238
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations