ZFIN ID: ZDB-GENE-040426-1279
Gene Name: dynactin 2 (p50)
Gene Symbol: dctn2    Nomenclature History

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Previous Names: p50/dynamitin (1), zgc:63867 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have motor activity. Involved in several processes, including P granule organization; neurogenesis; and photoreceptor cell maintenance. Predicted to localize to cytoplasm; microtubule cytoskeleton; and vesicle. Orthologous to human DCTN2 (dynactin subunit 2).
Genome Resources: Alliance (1),  Gene:394141 (1),  Ensembl(GRCz11):ENSDARG00000031388 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:63867]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
jj50 Point Mutation Unknown Cryptic Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45270 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dctn2 N/A 1
    MO2-dctn2 N/A 1
    DISEASE ASSOCIATED WITH dctn2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dctn2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process auditory receptor cell development (more)
    Cellular Component vesicle (more)
    Molecular Function motor activity (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dctn2-202 (1)    Ensembl 2035
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dctn2
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    tg(uas:dctn2-2a-egfp-caax) UAS 2ACAAXdctn2EGFP Danio rerio 1 1
    MARKER RELATIONSHIPS
    dctn2 Contained in: [BAC] CH211-125M22 (1)
    dctn2 Encodes: [cDNA] MGC:63867 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201166 (1) 2013 nt
    Genomic GenBank:BX950854 (1) 171896 nt
    Select Tool
    Polypeptide UniProtKB:F1QA97 (1) 405 aa
    Sequence Information (all 15)
    ORTHOLOGY for dctn2 ( Chr: 6 )
    CITATIONS (33)