| ZFIN ID: ZDB-GENE-040426-1221 |
| Gene Name: | heat shock cognate 70 | |||||||||||||
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| Gene Symbol: | hsc70 Nomenclature History |
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Attributions
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| Previous Name: | zgc:63663 | |||||||||||||
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| Gene Type: | protein_coding_gene | |||||||||||||
| Location: | Chr: 15 Mapping Details/Browsers | |||||||||||||
| Description: | Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and protein folding chaperone. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Predicted to localize to cytosol; nucleus; and plasma membrane. Is expressed in myotome. Orthologous to human HSPA2 (heat shock protein family A (Hsp70) member 2). | |||||||||||||
| Genome Resources: | Alliance (1), Gene:393586 (1), Ensembl(GRCz11):ENSDARG00000012381 (2) | |||||||||||||
| All Expression Data: | 7 figures from 2 publications |
| Directly Submitted Expression Data: | 6 figures (4 images) from Thisse et al., 2004 [MGC:63663] |
| Wild-type Stages, Structures: | Pharyngula:Prim-15 (30.0h-36.0h) to Adult (90d-730d, breeding adult) |
| High Throughput Expression: | GEO (1) , Expression Atlas (1) |
MUTATIONS AND SEQUENCE TARGETING REAGENTS
No data available
GENE ONTOLOGY
| Ontology | GO Term |
|---|---|
| Biological Process | cellular response to unfolded protein (more) |
| Cellular Component | cytoplasm (more) |
| Molecular Function | ATP binding (more) |
| Type | Name | Length (nt) | Analysis | |
|---|---|---|---|---|
| mRNA |
hsc70-201
(1)
|
2469 |
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| Browsers: UCSC, NCBI, Ensembl, ZFIN |
INTERACTIONS AND PATHWAYS
ANTIBODIES
No data available
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM hsc70
| Construct | Regulatory Regions | Coding Sequences | Species | Tg Lines | Publications |
|---|---|---|---|---|---|
| Tg(CMV:EGFP,hsc70:Cca.Ckm3) | hsc70 | EGFP | Cyprinus carpio, Danio rerio | 1 | 2 |
MARKER RELATIONSHIPS
| hsc70 Contained in: | [BAC] DKEY-238D18 (1) (order this) |
| hsc70 Encodes: | [cDNA] MGC:63663 (1) |
SEQUENCE INFORMATION
| Type | Accession # | Length (nt/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_200614 (1) | 2476 nt |
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| Genomic | GenBank:CR944667 (1) | 209310 nt | Blast at MegaBLAST |
| Polypeptide | UniProtKB:Q6PGX4 (1) | 647 aa |
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ORTHOLOGY for hsc70 (
Chr:
15
)
CITATIONS (23)