Gene

cisd1

ID

ZDB-GENE-040426-1162

Name

CDGSH iron sulfur domain 1

Symbol

cisd1 Nomenclature History

Previous Names

si:dkey-18n13.4
zgc:63561

Type

protein_coding_gene

Location

Chr: 13 Mapping Details/Browsers

Description

Predicted to enable 2 iron, 2 sulfur cluster binding activity and L-cysteine transaminase activity. Predicted to be involved in intracellular iron ion homeostasis. Predicted to act upstream of or within regulation of autophagy. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in mitochondrial outer membrane. Orthologous to human CISD1 (CDGSH iron sulfur domain 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:63561 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cisd1 Human Ortholog

No data available

Associated With cisd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR018967	Iron-binding zinc finger, CDGSH type
Family	IPR045131	CDGSH iron-sulfur domain-containing protein 1/2
Homologous_superfamily	IPR042216	MitoNEET, CDGSH iron-sulfur domain