ZFIN Gene: enpp2

ZFIN ID: ZDB-GENE-040426-1156

ZFIN ID: ZDB-GENE-040426-1156

Gene Name:

ectonucleotide pyrophosphatase/phosphodiesterase 2

Gene Symbol:

enpp2

Sequence Ontology ID :

SO:0000704

Previous Names:

atx (1), autotaxin (1), zgc:63550

Location:

Chr: 16 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Exhibits lysophospholipase activity and phosphoric diester hydrolase activity. Involved in several processes, including Kupffer's vesicle development; animal organ development; and oligodendrocyte ...

GENE EXPRESSION
All Expression Data:	8 figures from 5 publications
Wild-type Stages, Structures:	Cleavage:2-cell (0.75h-1.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
	axis brain chondrocyte cranial vasculature dorsal aorta floor plate head pectoral fin pharyngeal arch posterior cardinal vein shield spinal cord trabecula cranii whole organism anterior-posterior axis whole organism yolk syncytial layer

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa6410	Point Mutation	Unknown	Splice Site	ENU
sa36049	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa42664	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

Targeting reagents:

PHENOTYPE

Data:

17 figures from 5 publications

Observed in:

DISEASE ASSOCIATED WITH enpp2 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH enpp2 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cartilage development (more)
Cellular Component	extracellular space (more)
Molecular Function	lysophospholipase activity (more)

GO Terms (all 29)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR001212 (1) InterPro:IPR001604 (1) InterPro:IPR002591 (1) InterPro:IPR017850 (1) InterPro:IPR020436 (1) InterPro:IPR020821 (1) InterPro:IPR029881 (1) InterPro:IPR036024 (1)	PROSITE:PS00524 (1) PROSITE:PS50958 (1)	Pfam:PF01033 (1) Pfam:PF01223 (1) Pfam:PF01663 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	enpp2-201 (1)	3119	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Withdrawn Transcripts
mRNA	enpp2-001 (1)	3049	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
	enpp2-002 (1)	1219	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
	ottdart00000051883 (1)	3024	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIES

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM enpp2 No data available

MARKER RELATIONSHIPS

enpp2Contained in:	[BAC] CH211-93I7 (1) (order this), DKEY-59G8 (1) (order this)
enpp2Encodes:	[cDNA] MGC:63550 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_200603 (1)	3044bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CU104700 (1)	155195bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q6PGY9 (1)	850aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:81765 (1)

Sequence Information (all 14)

OTHER enpp2 GENE PAGES

Alliance (1)

Gene:100332039 (1)

VEGA:OTTDARG00000042849 (1)

Ensembl(GRCz11):ENSDARG00000011257 (2)

ORTHOLOGY for enpp2 (Chr: 16)

CITATIONS (25)

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