Gene

enpp2

ID
ZDB-GENE-040426-1156
Name
ectonucleotide pyrophosphatase/phosphodiesterase 2
Symbol
enpp2 Nomenclature History
Previous Names
  • atx (1)
  • autotaxin (1)
  • zgc:63550
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Exhibits lysophospholipase activity and phosphoric diester hydrolase activity. Involved in several processes, including Kupffer's vesicle development; animal organ development; and oligodendrocyte differentiation. Predicted to localize to extracellular space. Is expressed in several structures, including axial blood vessel; axis; central nervous system; head; and shield. Orthologous to human ENPP2 (ectonucleotide pyrophosphatase/phosphodiesterase 2).
Genome Resources
Note
None
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
17 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With enpp2 Human Ortholog
No data available
Associated With enpp2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001212 Somatomedin B domain
Domain IPR001604 DNA/RNA non-specific endonuclease
Domain IPR020436 Somatomedin B, chordata
Domain IPR020821 Extracellular Endonuclease, subunit A
Family IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
Family IPR029881 Ectonucleotide pyrophosphatase/phosphodiesterase family member 2
Homologous_superfamily IPR017850 Alkaline-phosphatase-like, core domain superfamily
Homologous_superfamily IPR036024 Somatomedin B-like domain superfamily
Domain Details Per Protein
Protein Length Alkaline-phosphatase-like, core domain superfamily DNA/RNA non-specific endonuclease Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 Extracellular Endonuclease, subunit A Somatomedin B, chordata Somatomedin B domain Somatomedin B-like domain superfamily Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
UniProtKB:Q6PGY9 850
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab4-enpp2 polyclonal Rabbit
  • IHC
  • WB
Abnova
3
Ab3-enpp2 polyclonal IgG Rabbit
  • WB
Cayman Chemical Company
2
Ab2-enpp2 polyclonal
  • WB
1
Ab1-enpp2 polyclonal Rat
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations