ZFIN ID: ZDB-GENE-040426-1039
Gene Name: eukaryotic translation initiation factor 2B, subunit 3 gamma
Gene Symbol: eif2b3
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:56473 (1)

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Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have nucleotidyltransferase activity and translation initiation factor activity; predicted to be involved in translational initiation; orthologous to human EIF2B3 (eukaryotic translation  ...
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6909645]
  4 figures (12 images) from Rauch et al., 2003 [fq32g07]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa32957 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH eif2b3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    leukoencephalopathy with vanishing white matter Leukoencephalopathy with vanishing white matter 603896
    DISEASE ASSOCIATED WITH eif2b3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process biosynthetic process (more)
    Molecular Function nucleotidyltransferase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005835 (1)
  • InterPro:IPR029044 (1)
  • Pfam:PF00483 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA eif2b3-001 (1) 1737
    eif2b3-002 (1) 698
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM eif2b3 No data available
    MARKER RELATIONSHIPS
    eif2b3Contained in: [BAC] CH211-226H23 (1) (order this)
    eif2b3Encodes: [EST] fq32g07 (1) (order this), IMAGE:6909645 (1) (order this)
    [cDNA] MGC:56473 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201074 (1) 1755bp
    Genomic GenBank:BX649493 (1) 175551bp
    Select Tool
    Polypeptide UniProtKB:Q7ZTY5 (1) 453aa
    Sequence Clusters UniGene:84039 (1)
    Sequence Information (all 15)
    OTHER eif2b3 GENE PAGES
  • Alliance (1)
  • Gene:394049 (1)
  • VEGA:OTTDARG00000019876 (1)
  • Ensembl(GRCz11):ENSDARG00000018106 (2)
  • ORTHOLOGY for eif2b3 (Chr: 2)
    CITATIONS (21)