ZFIN ID: ZDB-FISH-220120-18
Fish name: eif2b3ck156a/ck156a
Genotype: eif2b3ck156a/ck156a
Targeting Reagent: none
HUMAN DISEASE MODELED by eif2b3ck156a/ck156a
Human Disease Conditions Citations
leukoencephalopathy with vanishing white matter standard conditions (2)
GENE EXPRESSION
Gene expression in eif2b3ck156a/ck156a
RNA expression
Expressed Gene Structure Conditions Figures
abat standard conditions Figure 4 with image from Kim et al., 2021
apoeb standard conditions Fig. 3 from Lee et al., 2021
ass1 standard conditions Figure 4 with image from Kim et al., 2021
atf4a standard conditions Fig. S3 from Kim et al., 2021
atf6 standard conditions Fig. S3 from Kim et al., 2021
Fig. S4 from Lee et al., 2021
cad standard conditions Figure 4 with image from Kim et al., 2021
crybb1 standard conditions Fig. S4 from Kim et al., 2021
lonp1 standard conditions Figure 4 with image from Kim et al., 2021
mbpa standard conditions Figure 1 with image from Kim et al., 2021
Fig. 2 from Lee et al., 2021
nes standard conditions Figure 1 with image from Kim et al., 2021
olig2 standard conditions Figure 1 with image from Kim et al., 2021
Fig. 3Fig. S2 from Lee et al., 2021
psat1 standard conditions Fig. S2 from Kim et al., 2021
septin6 standard conditions Figure 4 with image from Kim et al., 2021
slc1a4 standard conditions Figure 4 with image from Kim et al., 2021
tp53 standard conditions Fig. S4 from Lee et al., 2021
vegfaa standard conditions Fig. 4 from Lee et al., 2021
vegfab standard conditions Fig. 4 from Lee et al., 2021
xbp1 standard conditions Fig. S2 from Kim et al., 2021
Fig. S4 from Lee et al., 2021
Protein expression No data available
Reporter gene expression No data available
PHENOTYPE
Phenotype in eif2b3ck156a/ck156a
Phenotype Conditions Figures
brain tp53 expression increased amount, abnormal standard conditions Fig. S4 from Lee et al., 2021
central nervous system glial cell (sensu Vertebrata) olig2 expression decreased amount, abnormal standard conditions Figure 1 with image from Kim et al., 2021
cranial ganglion mbpa expression decreased amount, abnormal standard conditions Fig. 2 from Lee et al., 2021
embryo development process quality, normal standard conditions Fig. 1 from Lee et al., 2021
eye decreased size, abnormal standard conditions Fig. 1 from Lee et al., 2021
eye monocyte increased amount, abnormal standard conditions Fig. 3 from Lee et al., 2021
forebrain olig2 expression decreased amount, abnormal standard conditions Fig. 3Fig. S2 from Lee et al., 2021
heart edematous, abnormal standard conditions Fig. 1 from Lee et al., 2021
intestine atf6 expression increased amount, abnormal standard conditions Fig. S4 from Lee et al., 2021
intestine xbp1 expression increased amount, abnormal standard conditions Fig. S4 from Lee et al., 2021
lens decreased size, abnormal standard conditions Fig. S4 from Kim et al., 2021
liver xbp1 expression increased amount, abnormal standard conditions Fig. S4 from Lee et al., 2021
liver atf6 expression increased amount, abnormal standard conditions Fig. S4 from Lee et al., 2021
microglia differentiation disrupted, abnormal standard conditions Fig. 3 from Lee et al., 2021
microglial cell apoeb expression decreased amount, abnormal standard conditions Fig. 3 from Lee et al., 2021
microglial cell decreased amount, abnormal standard conditions Fig. 3 from Lee et al., 2021
midbrain vegfaa expression increased amount, abnormal standard conditions Fig. 4 from Lee et al., 2021
midbrain monocyte increased amount, abnormal standard conditions Fig. 3 from Lee et al., 2021
midbrain neuronal stem cell nes expression increased amount, abnormal standard conditions Figure 1 with image from Kim et al., 2021
midbrain hindbrain boundary ass1 expression decreased amount, abnormal standard conditions Figure 4 with image from Kim et al., 2021
midbrain hindbrain boundary cad expression decreased amount, abnormal standard conditions Figure 4 with image from Kim et al., 2021
midbrain hindbrain boundary septin6 expression decreased amount, abnormal standard conditions Figure 4 with image from Kim et al., 2021
midbrain hindbrain boundary atf6 expression increased amount, abnormal standard conditions Fig. S3 from Kim et al., 2021
midbrain hindbrain boundary lonp1 expression increased amount, abnormal standard conditions Figure 4 with image from Kim et al., 2021
midbrain hindbrain boundary slc1a4 expression increased amount, abnormal standard conditions Figure 4 with image from Kim et al., 2021
midbrain hindbrain boundary xbp1 expression increased amount, abnormal standard conditions Fig. S2 from Kim et al., 2021
midbrain hindbrain boundary psat1 expression increased amount, abnormal standard conditions Fig. S2 from Kim et al., 2021
midbrain hindbrain boundary atf4a expression increased amount, abnormal standard conditions Fig. S3 from Kim et al., 2021
midbrain hindbrain boundary abat expression increased amount, abnormal standard conditions Figure 4 with image from Kim et al., 2021
motor behavior process quality, normal standard conditions Fig. 2 from Lee et al., 2021
motor neuron morphology, normal standard conditions Fig. 2 from Lee et al., 2021
nervous system myelin sheath mbpa expression decreased amount, abnormal standard conditions Figure 1 with image from Kim et al., 2021
pancreas xbp1 expression increased amount, abnormal standard conditions Fig. S4 from Lee et al., 2021
pancreas atf6 expression increased amount, abnormal standard conditions Fig. S4 from Lee et al., 2021
posterior lateral line nerve mbpa expression decreased amount, abnormal standard conditions Fig. 2 from Lee et al., 2021
retina olig2 expression decreased amount, abnormal standard conditions Fig. 3Fig. S2 from Lee et al., 2021
whole organism dead, abnormal standard conditions Fig. 1 from Lee et al., 2021
whole organism decreased life span, abnormal standard conditions Fig. 1 from Lee et al., 2021

CITATIONS  (2)