ZFIN ID: ZDB-GENE-040426-1021
Gene Name: tetratricopeptide repeat domain 4
Gene Symbol: ttc4    Nomenclature History

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Previous Names: zgc:56411, zgc:86801

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have actin binding activity. Involved in cilium assembly; determination of heart left/right asymmetry; and otolith morphogenesis. Orthologous to human TTC4 (tetratricopeptide repeat domain 4).
Genome Resources: Alliance (1),  Gene:393981 (1),  Ensembl(GRCz11):ENSDARG00000044405 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:56411]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la029213Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ttc4 N/A 1
    DISEASE ASSOCIATED WITH ttc4 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ttc4 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cilium assembly (more)
    Cellular Component cellular_component (more)
    Molecular Function actin binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ttc4-201 (1)    Ensembl 2024
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ttc4 No data available
    MARKER RELATIONSHIPS
    ttc4 Contained in: [BAC] DKEY-218B7 (1) (order this)
    ttc4 Encodes: [cDNA] MGC:56411 (1), MGC:86801
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001002122 (1) 2023 nt
    Genomic GenBank:BX088595 (1) 143341 nt
    Select Tool
    Polypeptide UniProtKB:F1QHZ3 (1) 402 aa
    Sequence Information (all 18)
    ORTHOLOGY for ttc4 ( Chr: 6 )
    CITATIONS (19)