ZFIN ID: ZDB-GENE-040329-3
Gene Name: monoamine oxidase
Gene Symbol: mao    Nomenclature History

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Previous Names: wu:fb68b05, wu:fo76d11, wu:fq38g06, Z-MAO (1), zgc:85761

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Exhibits primary amine oxidase activity. Involved in cellular biogenic amine catabolic process. Predicted to localize to integral component of membrane and mitochondrial outer membrane. Is expressed in brain; digestive system; gill; heart; and neurons. Human ortholog(s) of this gene implicated in Brunner Syndrome; alcohol use disorder; autism spectrum disorder; neurodegenerative disease (multiple); and panic disorder. Orthologous to several human genes including MAOB (monoamine oxidase B).
Genome Resources: Alliance (1),  Gene:404730 (1),  Ensembl(GRCz11):ENSDARG00000023712 (2)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH mao HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Brunner Syndrome Alliance Brunner syndrome 300615
{Antisocial behavior} 300615
DISEASE ASSOCIATED WITH mao VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular biogenic amine catabolic process (more)
Cellular Component integral component of membrane (more)
Molecular Function primary amine oxidase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA mao-201 (1)    Ensembl 4420
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM mao No data available
MARKER RELATIONSHIPS
mao Contained in: [BAC] CH211-222M21 (1)
mao Encodes: [EST] fb68b05 (1), fo76d11, fq38g06 (1) (order this), IMAGE:6793010
[cDNA] MGC:85761 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_212827 (1) 4456 nt
Genomic GenBank:BX572627 (1) 209758 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q6NSN2 (1) 522 aa
Sequence Information (all 18)
ORTHOLOGY for mao ( Chr: 9 )
CITATIONS (58)