Gene
mao
- ID
- ZDB-GENE-040329-3
- Name
- monoamine oxidase
- Symbol
- mao Nomenclature History
- Previous Names
-
- wu:fb68b05
- wu:fo76d11
- wu:fq38g06
- Z-MAO (1)
- zgc:85761
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Exhibits primary amine oxidase activity. Involved in cellular biogenic amine catabolic process. Predicted to localize to integral component of membrane and mitochondrial outer membrane. Human ortholog(s) of this gene implicated in Brunner Syndrome; alcohol use disorder; autism spectrum disorder; neurodegenerative disease (multiple); and panic disorder. Is expressed in brain; digestive system; gill; heart; and neurons. Orthologous to several human genes including MAOB (monoamine oxidase B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 23 figures from 12 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85761 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 8 figures from Baronio et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Brunner Syndrome | Alliance | Brunner syndrome | 300615 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Amine oxidase | FAD/NAD(P)-binding domain superfamily | Flavin amine oxidase | Flavin Monoamine Oxidase |
|---|---|---|---|---|---|
|
UniProtKB:Q6NSN2
|
522 |
Interactions and Pathways
No data available
Plasmids
No data available