Gene
aplp1
- ID
- ZDB-GENE-040319-1
- Name
- amyloid beta (A4) precursor-like protein 1
- Symbol
- aplp1 Nomenclature History
- Previous Names
-
- aplp
- im:7153266
- wu:fj55h01
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have heparin binding activity and transition metal ion binding activity. Predicted to localize to integral component of membrane. Is expressed in central nervous system; cranial ganglion; neurons; retina; and retinal ganglion cell layer. Orthologous to human APLP1 (amyloid beta precursor like protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7153266 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019744 | Amyloidogenic glycoprotein, copper-binding domain conserved site |
| Conserved_site | IPR019745 | Amyloidogenic glycoprotein, intracellular domain, conserved site |
| Domain | IPR008154 | Amyloidogenic glycoprotein, extracellular |
| Domain | IPR011178 | Amyloidogenic glycoprotein, copper-binding |
| Domain | IPR015849 | Amyloidogenic glycoprotein, heparin-binding |
| Domain | IPR019543 | Beta-amyloid precursor protein C-terminal |
| Domain | IPR024329 | Amyloidogenic glycoprotein, E2 domain |
| Family | IPR008155 | Amyloidogenic glycoprotein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR036176 | E2 domain superfamily |
| Homologous_superfamily | IPR036454 | Amyloidogenic glycoprotein, heparin-binding domain superfamily |
| Homologous_superfamily | IPR036669 | Amyloidogenic glycoprotein, copper-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Amyloidogenic glycoprotein | Amyloidogenic glycoprotein, copper-binding | Amyloidogenic glycoprotein, copper-binding domain conserved site | Amyloidogenic glycoprotein, copper-binding domain superfamily | Amyloidogenic glycoprotein, E2 domain | Amyloidogenic glycoprotein, extracellular | Amyloidogenic glycoprotein, heparin-binding | Amyloidogenic glycoprotein, heparin-binding domain superfamily | Amyloidogenic glycoprotein, intracellular domain, conserved site | Beta-amyloid precursor protein C-terminal | E2 domain superfamily | PH-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZZT2
|
357 | ||||||||||||
|
UniProtKB:A0A0R4IFK2
|
702 | ||||||||||||
|
UniProtKB:A0A0R4IXG2
|
723 |
Interactions and Pathways
No data available
Plasmids
No data available