Gene
aplp1
- ID
- ZDB-GENE-040319-1
- Name
- amyloid beta (A4) precursor-like protein 1
- Symbol
- aplp1 Nomenclature History
- Previous Names
-
- aplp
- im:7153266
- wu:fj55h01
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable alpha-2A adrenergic receptor binding activity; alpha-2B adrenergic receptor binding activity; and alpha-2C adrenergic receptor binding activity. Predicted to be involved in axonogenesis and central nervous system development. Predicted to be located in endomembrane system and membrane. Predicted to be active in Golgi apparatus and plasma membrane. Is expressed in nervous system. Orthologous to human APLP1 (amyloid beta precursor like protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7153266 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019744 | Amyloidogenic glycoprotein, copper-binding domain conserved site |
| Conserved_site | IPR019745 | Amyloidogenic glycoprotein, intracellular domain, conserved site |
| Domain | IPR008154 | Amyloidogenic glycoprotein, extracellular |
| Domain | IPR011178 | Amyloidogenic glycoprotein, copper-binding |
| Domain | IPR015849 | Amyloidogenic glycoprotein, heparin-binding |
| Domain | IPR019543 | Beta-amyloid precursor protein C-terminal |
| Domain | IPR024329 | Amyloidogenic glycoprotein, E2 domain |
| Family | IPR008155 | Amyloidogenic glycoprotein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR036176 | E2 domain superfamily |
| Homologous_superfamily | IPR036454 | Amyloidogenic glycoprotein, heparin-binding domain superfamily |
| Homologous_superfamily | IPR036669 | Amyloidogenic glycoprotein, copper-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Amyloidogenic glycoprotein | Amyloidogenic glycoprotein, copper-binding | Amyloidogenic glycoprotein, copper-binding domain conserved site | Amyloidogenic glycoprotein, copper-binding domain superfamily | Amyloidogenic glycoprotein, E2 domain | Amyloidogenic glycoprotein, extracellular | Amyloidogenic glycoprotein, heparin-binding | Amyloidogenic glycoprotein, heparin-binding domain superfamily | Amyloidogenic glycoprotein, intracellular domain, conserved site | Beta-amyloid precursor protein C-terminal | E2 domain superfamily | PH-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A0R4IXG2 | InterPro | 723 |
Interactions and Pathways
No data available
Plasmids
No data available