Gene

aplp1

ID
ZDB-GENE-040319-1
Name
amyloid beta (A4) precursor-like protein 1
Symbol
aplp1 Nomenclature History
Previous Names
  • aplp
  • im:7153266
  • wu:fj55h01
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have heparin binding activity and transition metal ion binding activity. Predicted to localize to integral component of membrane. Is expressed in central nervous system; cranial ganglion; neurons; retina; and retinal ganglion cell layer. Orthologous to human APLP1 (amyloid beta precursor like protein 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aplp1 Human Ortholog
No data available
Associated With aplp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019744 Amyloidogenic glycoprotein, copper-binding domain conserved site
Conserved_site IPR019745 Amyloidogenic glycoprotein, intracellular domain, conserved site
Domain IPR008154 Amyloidogenic glycoprotein, extracellular
Domain IPR011178 Amyloidogenic glycoprotein, copper-binding
Domain IPR015849 Amyloidogenic glycoprotein, heparin-binding
Domain IPR019543 Beta-amyloid precursor protein C-terminal
Domain IPR024329 Amyloidogenic glycoprotein, E2 domain
Family IPR008155 Amyloidogenic glycoprotein
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR036176 E2 domain superfamily
Homologous_superfamily IPR036454 Amyloidogenic glycoprotein, heparin-binding domain superfamily
Homologous_superfamily IPR036669 Amyloidogenic glycoprotein, copper-binding domain superfamily
Domain Details Per Protein
Protein Length Amyloidogenic glycoprotein Amyloidogenic glycoprotein, copper-binding Amyloidogenic glycoprotein, copper-binding domain conserved site Amyloidogenic glycoprotein, copper-binding domain superfamily Amyloidogenic glycoprotein, E2 domain Amyloidogenic glycoprotein, extracellular Amyloidogenic glycoprotein, heparin-binding Amyloidogenic glycoprotein, heparin-binding domain superfamily Amyloidogenic glycoprotein, intracellular domain, conserved site Beta-amyloid precursor protein C-terminal E2 domain superfamily PH-like domain superfamily
UniProtKB:Q7ZZT2 357
UniProtKB:A0A0R4IXG2 723
UniProtKB:A0A0R4IFK2 702
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations