Gene
aplp1
- ID
- ZDB-GENE-040319-1
- Name
- amyloid beta (A4) precursor-like protein 1
- Symbol
- aplp1 Nomenclature History
- Previous Names
-
- aplp
- im:7153266
- wu:fj55h01
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable heparin binding activity and transition metal ion binding activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in central nervous system; cranial ganglion; neurons; retina; and retinal ganglion cell layer. Orthologous to human APLP1 (amyloid beta precursor like protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1) UCSC scRNA-seq (1)
- Thisse Expression Data
-
- IMAGE:7153266 (10 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019744 | Amyloidogenic glycoprotein, copper-binding domain conserved site |
| Conserved_site | IPR019745 | Amyloidogenic glycoprotein, intracellular domain, conserved site |
| Domain | IPR008154 | Amyloidogenic glycoprotein, extracellular |
| Domain | IPR011178 | Amyloidogenic glycoprotein, copper-binding |
| Domain | IPR015849 | Amyloidogenic glycoprotein, heparin-binding |
| Domain | IPR019543 | Beta-amyloid precursor protein C-terminal |
| Domain | IPR024329 | Amyloidogenic glycoprotein, E2 domain |
| Family | IPR008155 | Amyloidogenic glycoprotein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR036176 | E2 domain superfamily |
| Homologous_superfamily | IPR036454 | Amyloidogenic glycoprotein, heparin-binding domain superfamily |
| Homologous_superfamily | IPR036669 | Amyloidogenic glycoprotein, copper-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Amyloidogenic glycoprotein | Amyloidogenic glycoprotein, copper-binding | Amyloidogenic glycoprotein, copper-binding domain conserved site | Amyloidogenic glycoprotein, copper-binding domain superfamily | Amyloidogenic glycoprotein, E2 domain | Amyloidogenic glycoprotein, extracellular | Amyloidogenic glycoprotein, heparin-binding | Amyloidogenic glycoprotein, heparin-binding domain superfamily | Amyloidogenic glycoprotein, intracellular domain, conserved site | Beta-amyloid precursor protein C-terminal | E2 domain superfamily | PH-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZZT2
|
357 | ||||||||||||
|
UniProtKB:A0A0R4IFK2
|
702 | ||||||||||||
|
UniProtKB:A0A0R4IXG2
|
723 |
Interactions and Pathways
No data available
Plasmids
No data available