ZFIN Gene: aplp1

ZFIN ID: ZDB-GENE-040319-1

ZFIN ID: ZDB-GENE-040319-1

Gene Name:

amyloid beta (A4) precursor-like protein 1

Gene Symbol:

aplp1

Sequence Ontology ID :

SO:0001217

Previous Names:

aplp, im:7153266, wu:fj55h01

Location:

Chr: 15 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have heparin binding activity and transition metal ion binding activity. Predicted to localize to the integral component of membrane. Is expressed in central nervous system; cranial ...

GENE EXPRESSION
Directly Submitted Expression Data:	6 figures (10 images) from Thisse et al., 2004 [IMAGE:7153266]
Wild-type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
	central nervous system cranial ganglion neuron retina retinal ganglion cell layer unspecified
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa24738	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

PHENOTYPE No data available

DISEASE ASSOCIATED WITH aplp1 HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH aplp1 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Cellular Component	integral component of membrane (more)
Molecular Function	heparin binding (more)

GO Terms (all 4)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR008154 (1) InterPro:IPR008155 (1) InterPro:IPR011178 (1) InterPro:IPR011993 (1) InterPro:IPR015849 (1) InterPro:IPR019543 (1) InterPro:IPR019744 (1) InterPro:IPR019745 (1) InterPro:IPR024329 (1) InterPro:IPR036176 (1) InterPro:IPR036454 (1) InterPro:IPR036669 (1)	PROSITE:PS00319 (1) PROSITE:PS00320 (1)	Pfam:PF02177 (1) Pfam:PF10515 (1) Pfam:PF12924 (1) Pfam:PF12925 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	aplp1-202 (1)	5439	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM aplp1 No data available

MARKER RELATIONSHIPS

aplp1 Contained in:	[BAC] CH211-147F13 (1) (order this)
aplp1 Encodes:	[EST] fj55h01 (1), IMAGE:7153266 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:XM_001342885 (1)	5661 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR848749 (1)	161648 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A0R4IXG2 (1)	723 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:155640 (1)

Sequence Information (all 31)

OTHER aplp1 GENE PAGES

Alliance (1)

Gene:404233 (1)

VEGA:OTTDARG00000020821 (1)

Ensembl(GRCz11):ENSDARG00000098368 (1)

ORTHOLOGY for aplp1 ( Chr: 15 )

CITATIONS (18)

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