ZFIN ID: ZDB-GENE-040310-6
Gene Name: connexin 52.6
Gene Symbol: cx52.6    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Exhibits gap junction hemi-channel activity. Predicted to be involved in cell communication. Localizes to the gap junction. Is expressed in brain; heart; and retina. Orthologous to human GJA10 (gap junction protein alpha 10).
Genome Resources: Alliance (1),  Gene:404207 (1),  Ensembl(GRCz11):ENSDARG00000034930 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu2504 Point Mutation Unknown Premature Stop ENU
sa43436 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-cx52.6 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cx52.6 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cx52.6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell communication (more)
    Cellular Component gap junction (more)
    Molecular Function gap junction channel activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR017990 Connexin, conserved site
    Domain IPR013092 Connexin, N-terminal
    Domain IPR019570 Gap junction protein, cysteine-rich domain
    Family IPR000500 Connexin
    Homologous_superfamily IPR038359 Connexin, N-terminal domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cx52.6-201 (1)    Ensembl 2114
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab2-cx52.6 polyclonal Rabbit IHC 1
    Ab1-cx52.6 polyclonal Rabbit IHC 3
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cx52.6
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(cx52.6:EGFP) cx52.6 EGFP Danio rerio 1 1
    MARKER RELATIONSHIPS
    cx52.6 Contained in: [BAC] DKEYP-117E10 (1)
    cx52.6 Encodes: [EST] eu908 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_212819 (1) 1401 nt
    Genomic GenBank:BX510339 (1) 70879 nt
    Select Tool
    Polypeptide UniProtKB:F6NP30 (1) 474 aa
    Sequence Information (all 13)
    ORTHOLOGY for cx52.6 ( Chr: 20 )
    CITATIONS (36)