Gene

traf4a

ID
ZDB-GENE-040308-1
Name
tnf receptor-associated factor 4a
Symbol
traf4a Nomenclature History
Previous Names
  • traf4l
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to enable tumor necrosis factor receptor binding activity and zinc ion binding activity. Acts upstream of or within establishment of epithelial cell apical/basal polarity; optic cup morphogenesis involved in camera-type eye development; and optic vesicle elongation. Predicted to be located in cytoplasm. Is expressed in several structures, including axial blood vessel; digestive system; immature eye; mesoderm; and nervous system. Orthologous to human TRAF4 (TNF receptor associated factor 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from Hehr et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With traf4a Human Ortholog
No data available
Associated With traf4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR001293 Zinc finger, TRAF-type
Domain IPR001841 Zinc finger, RING-type
Domain IPR002083 MATH/TRAF domain
Domain IPR018957 Zinc finger, C3HC4 RING-type
Domain IPR037307 TNF receptor-associated factor 4, MATH domain
Family IPR012227 TNF receptor-associated factor TRAF, metazoa
Family IPR027138 TNF receptor-associated factor 4
Family IPR043211 TNF receptor-associated factor TRAF
Homologous_superfamily IPR008974 TRAF-like
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length MATH/TRAF domain TNF receptor-associated factor 4 TNF receptor-associated factor 4, MATH domain TNF receptor-associated factor TRAF TNF receptor-associated factor TRAF, metazoa TRAF-like Zinc finger, C3HC4 RING-type Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site Zinc finger, TRAF-type
UniProtKB:Q7T1K2 470
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations