ZFIN ID: ZDB-GENE-040308-1
Gene Name: tnf receptor-associated factor 4a
Gene Symbol: traf4a    Nomenclature History

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Previous Name: traf4l

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have tumor necrosis factor receptor binding activity and zinc ion binding activity. Predicted to be involved in protein K63-linked ubiquitination; regulation of intracellular signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to localize to plasma membrane signaling receptor complex. Is expressed in several structures, including axial blood vessel; digestive system; immature eye; mesoderm; and nervous system. Orthologous to human TRAF4 (TNF receptor associated factor 4).
Genome Resources: Alliance (1),  Gene:404045 (1),  Ensembl(GRCz11):ENSDARG00000003963 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ca301 Small Deletion Unknown Unknown CRISPR
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-traf4a 2
MO1-traf4a N/A 1
MO2-traf4a N/A 1
DISEASE ASSOCIATED WITH traf4a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH traf4a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process activation of NF-kappaB-inducing kinase activity (more)
Cellular Component cytoplasm (more)
Molecular Function metal ion binding (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA traf4a-201 (1)    Ensembl 3072
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM traf4a No data available
MARKER RELATIONSHIPS
traf4a Contained in: [BAC] CH211-187B9 (1), DKEY-81N5 (1) (order this)
traf4a Encodes: [EST] eu286 (1)
[cDNA] MGC:77418 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_205762 (1) 3090 nt
Genomic GenBank:CR392353 (1) 183599 nt
Select Tool
Polypeptide UniProtKB:Q7T1K2 (1) 470 aa
Sequence Information (all 14)
ORTHOLOGY for traf4a ( Chr: 15 )
CITATIONS (28)