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General Information
ZIRC
ZFIN ID: ZDB-GENE-040305-1
Gene Name: nitric oxide synthase 2a, inducible
Gene Symbol: nos2a
Sequence Ontology ID : SO:0001217

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Previous Names: inosa, nos2 (1), inducible nitric oxide synthase a, si:dkey-57m14.4

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have NADPH-hemoprotein reductase activity; coenzyme binding activity; and nitric-oxide synthase activity. Involved in response to glucose; response to lipopolysaccharide; and response to  ...
GENE EXPRESSION
All Expression Data: 21 figures from 12 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu740]
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025102Tg Transgenic Insertion Unknown Unknown DNA
sa14328 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa14427 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa38498 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH nos2a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    essential hypertension {Hypertension, susceptibility to} 145500
    {Malaria, resistance to} 611162
    DISEASE ASSOCIATED WITH nos2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process response to glucose (more)
    Cellular Component cytosol (more)
    Molecular Function calmodulin binding (more)
    GO Terms (all 23)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA nos2a-002 (1) 523
    nos2a-003 (1) 402
    mRNA nos2a-202 (1) 3857
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nos2a No data available
    MARKER RELATIONSHIPS
    nos2a Contained in: [BAC] DKEY-57M14 (order this)
    nos2a Encodes: [EST] eu740 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001104937 (1) 3382 bp
    Genomic GenBank:BX950211 (1) 134143 bp
    Select Tool
    Polypeptide UniProtKB:A2BIN8 (1) 1079 aa
    Sequence Clusters UniGene:85064 (1)
    Sequence Information (all 18)
    ORTHOLOGY for nos2a ( Chr: 5 )
    CITATIONS (84)