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General Information
ZIRC
ZFIN ID: ZDB-GENE-040219-3
Gene Name: MYD88 innate immune signal transduction adaptor
Gene Symbol: myd88
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: zMyD88 (1), zgc:103541

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have Toll-like receptor binding activity. Involved in several processes, including neutrophil activation involved in immune response; neutrophil chemotaxis; and response to bacterium.  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3568 Point Mutation Unknown Premature Stop ENU
w187 Small Deletion Unknown Frameshift, Premature Stop TALEN
xt29 Small Deletion Unknown Unknown CRISPR
b1354 Small Deletion Exon 1 Premature Stop CRISPR
Targeting reagents:
DISEASE ASSOCIATED WITH myd88 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
lymphoplasmacytic lymphoma Macroglobulinemia, Waldenstrom, somatic 153600
Pyogenic bacterial infections, recurrent, due to MYD88 deficiency 612260
DISEASE ASSOCIATED WITH myd88 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neutrophil chemotaxis (more)
Cellular Component cytoplasm (more)
Molecular Function protein binding (more)
GO Terms (all 21)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA myd88-201 (1) 1485
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM myd88
MARKER RELATIONSHIPS
myd88Contained in: [BAC] CH211-227L2 (1) (order this)
myd88Encodes: [cDNA] MGC:103541 (1) (order this), MGC:191817 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_212814 (1) 1369bp
Genomic GenBank:BX247944 (1) 155665bp
Select Tool
Polypeptide UniProtKB:A0A0R4I9A6 (1) 284aa
Sequence Clusters UniGene:134592 (1)
Sequence Information (all 22)
ORTHOLOGY for myd88 (Chr: 24)
CITATIONS (110)