ZFIN ID: ZDB-GENE-040219-3
Gene Name: MYD88 innate immune signal transduction adaptor
Gene Symbol: myd88
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: zMyD88 (1), zgc:103541

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(Including Attributions)
Location: Chr: 24 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 19 figures from 13 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3568 Point Mutation Unknown Premature Stop ENU
w187 Small Deletion Unknown Frameshift, Premature Stop TALEN
xt29 Small Deletion Unknown Unknown CRISPR
Targeting reagents:
PHENOTYPE
Data: 8 figures from 4 publications
Observed in:
DISEASE ASSOCIATED WITH myd88 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
lymphoplasmacytic lymphoma Macroglobulinemia, Waldenstrom, somatic 153600
Pyogenic bacterial infections, recurrent, due to MYD88 deficiency 612260
DISEASE ASSOCIATED WITH myd88 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process neutrophil chemotaxis (more)
Cellular Component cytoplasm (more)
Molecular Function protein binding (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000157 (1)
  • InterPro:IPR000488 (1)
  • InterPro:IPR011029 (1)
  • InterPro:IPR017281 (1)
  • InterPro:IPR034249 (1)
  • InterPro:IPR035897 (1)
  • PROSITE:PS50017 (1)
  • PROSITE:PS50104 (1)
  • Pfam:PF00531 (1)
  • Pfam:PF01582 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA myd88-001 (1) 1485
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM myd88
    MARKER RELATIONSHIPS
    myd88Contained in: [BAC] CH211-227L2 (1) (order this)
    myd88Encodes: [cDNA] MGC:103541 (1) (order this), MGC:191817 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212814 (1) 1369bp
    Genomic GenBank:BX247944 (1) 155665bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4I9A6 (1) 284aa
    Sequence Clusters UniGene:134592 (1)
    Sequence Information (all 22)
    OTHER myd88 GENE PAGES
  • Alliance (1)
  • Gene:403145 (1)
  • VEGA:OTTDARG00000021382 (1)
  • Ensembl(GRCz11):ENSDARG00000010169 (2)
  • ORTHOLOGY for myd88 (Chr: 24)
    CITATIONS (103)