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ZIRC
ZFIN ID: ZDB-GENE-040219-11
Gene Name: toll-like receptor 7
Gene Symbol: tlr7    Nomenclature History

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Previous Name: TLR7A (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have single-stranded RNA binding activity and transmembrane signaling receptor activity. Predicted to be involved in defense response to other organism and toll-like receptor signaling pathway. Predicted to localize to the cytoskeleton and integral component of membrane. Is expressed in several structures, including blood; heart; integument; liver; and pleuroperitoneal region. Orthologous to human TLR7 (toll like receptor 7).
Genome Resources: Alliance (1),  Gene:100534776 (1)
GENE EXPRESSION
All Expression Data: 5 figures from 4 publications
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7215 Point Mutation Unknown Premature Stop ENU
sa11566 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31752 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41556 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44716 Point Mutation Unknown Unknown ENU
    zf2185 Small Deletion Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-tlr7 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH tlr7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH tlr7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process defense response to virus (more)
    Cellular Component cytoskeleton (more)
    Molecular Function single-stranded RNA binding (more)
    GO Terms (all 12)
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM tlr7 No data available
    MARKER RELATIONSHIPS No data available
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_021479060 (1)
    Genomic GenBank:CU914164 (1) 141464 bp
    Select Tool
    Polypeptide UniProtKB:F1QXP3 (1) 1221 aa
    Sequence Clusters UniGene:156645 (1)
    Sequence Information (all 9)
    ORTHOLOGY for tlr7 ( Chr: 9 )
    CITATIONS (23)