Gene

tlr9

ID
ZDB-GENE-040219-10
Name
toll-like receptor 9
Symbol
tlr9 Nomenclature History
Previous Names
  • TIR9 (1)
  • sb:eu392
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have pattern recognition receptor activity. Involved in antibacterial humoral response and toll-like receptor signaling pathway. Localizes to endoplasmic reticulum. Is expressed in blood; heart; liver; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in several diseases, including allergic bronchopulmonary aspergillosis; cystic fibrosis; glomerulonephritis (multiple); hepatitis B; and lung disease (multiple). Orthologous to human TLR9 (toll like receptor 9).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tlr9 Human Ortholog
No data available
Associated With tlr9 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000157 Toll/interleukin-1 receptor homology (TIR) domain
Domain IPR000483 Cysteine-rich flanking region, C-terminal
Family IPR027181 Toll-like receptor 9
Homologous_superfamily IPR032675 Leucine-rich repeat domain superfamily
Homologous_superfamily IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily
Repeat IPR001611 Leucine-rich repeat
Repeat IPR003591 Leucine-rich repeat, typical subtype
Repeat IPR026906 BspA type Leucine rich repeat region
Domain Details Per Protein
Protein Length BspA type Leucine rich repeat region Cysteine-rich flanking region, C-terminal Leucine-rich repeat Leucine-rich repeat domain superfamily Leucine-rich repeat, typical subtype Toll/interleukin-1 receptor homology (TIR) domain Toll/interleukin-1 receptor homology (TIR) domain superfamily Toll-like receptor 9
UniProtKB:B5LCC6 259
UniProtKB:B5LCC5 236
UniProtKB:B3DJW3 1057
UniProtKB:Q6TQH3 110
UniProtKB:A0A2R8QA47 1069
UniProtKB:F1QY61 1057
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations