ZFIN ID: ZDB-GENE-040120-4
Gene Name: dihydrolipoamide dehydrogenase
Gene Symbol: dldh

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Previous Names: fb24b05, wu:fb24b05 (1)

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(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (10 images) from Thisse et al., 2004 [IMAGE:7151702]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
  adaxial cell, immature eye, liver, midbrain (all 10) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-dldh (1)
PHENOTYPE
Data: Fig. 4 from Ke├čler et al., 2015
Observed in: heart contraction, pericardium
DISEASE ASSOCIATED WITH dldh HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
maple syrup urine disease Dihydrolipoamide dehydrogenase deficiency 246900
GENE ONTOLOGY
Ontology GO Term
Biological Process heart contraction (more)
Molecular Function dihydrolipoyl dehydrogenase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004099 (1)
  • InterPro:IPR006258 (1)
  • InterPro:IPR012999 (1)
  • InterPro:IPR016156 (1)
  • InterPro:IPR023753 (1)
  • PROSITE:PS00076 (1)
  • Pfam:PF02852 (1)
  • Pfam:PF07992 (1)
  • EC:1.8.1.4 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dldh-001 (1) 1806
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dldh No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    dldhContained in: [BAC] DKEY-42P14 (1) (order this)
    dldhEncodes: [EST] fb24b05, IMAGE:7151702 (1) (order this)
    [cDNA] MGC:55583 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_201506 (1) 1805bp
    Genomic GenBank:CR376804 (1) 117107bp
    Select Tool
    Polypeptide UniProtKB:Q6TNU6 (1) 507aa
    Sequence Clusters UniGene:76179 (1)
    Sequence Information (all 14)
    OTHER dldh GENE PAGES
  • Gene:399479 (1)
  • VEGA:OTTDARG00000021231 (1)
  • Ensembl(GRCz10):ENSDARG00000008785 (1)
  • ORTHOLOGY for dldh (Chr: 25)
    Species Symbol Chromosome Accession # Evidence
    Human DLD 7
  • Gene:1738
  • OMIM:238331
  • HGNC:2898
  • Amino acid sequence comparison (2)
    Download Curated Orthology
    CITATIONS (18)