ZFIN Gene: gfi1ab

ZFIN ID: ZDB-GENE-040116-8

ZFIN ID: ZDB-GENE-040116-8

Gene Name:

growth factor independent 1A transcription repressor b

Gene Symbol:

gfi1ab

Sequence Ontology ID :

SO:0000704

Previous Names:

gfi1.2, gfi1, gfi1b

Location:

Chr: 6 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have DNA binding activity and DNA-binding activity transcription factor activity; involved in peripheral nervous system development; predicted to localize to the nucleus; orthologous to ...

GENE EXPRESSION
All Expression Data:	30 figures from 17 publications
Wild-type Stages, Structures:	Segmentation:5-9 somites (11.66h-14.0h) to Adult (90d-730d, breeding adult)
	anterior lateral mesoderm brain diencephalon hair cell inner ear midbrain neuromast otic placode parapineal organ neuron parapineal organ pineal complex posterior lateral line system telencephalon unspecified ventral wall of dorsal aorta

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa38552	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa40706	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

PHENOTYPE No data available

DISEASE ASSOCIATED WITH gfi1ab HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
	?Neutropenia, nonimmune chronic idiopathic, of adults	607847
	?Neutropenia, nonimmune chronic idiopathic, of adults	607847
	?Neutropenia, severe congenital 2, autosomal dominant	613107
	?Neutropenia, severe congenital 2, autosomal dominant	613107

DISEASE ASSOCIATED WITH gfi1ab VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	peripheral nervous system development (more)
Cellular Component	nucleus (more)
Molecular Function	metal ion binding (more)

GO Terms (all 6)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR013087 (1) InterPro:IPR036236 (1)	PROSITE:PS00028 (1) PROSITE:PS50157 (1)	Pfam:PF00096 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	gfi1ab-201 (1)	1228	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM gfi1ab No data available

MARKER RELATIONSHIPS

gfi1abContained in:	[BAC] DKEY-11H2 (1) (order this)
gfi1abEncodes:	[cDNA] MGC:194663 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_201338 (1)	1191bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX004878 (1)	254657bp	Blast at MegaBLAST
Polypeptide	UniProtKB:F1QKD4 (1)	396aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:89476 (1)

Sequence Information (all 13)

OTHER gfi1ab GENE PAGES

Alliance (1)

Gene:798697 (1)

VEGA:OTTDARG00000019805 (1)

Ensembl(GRCz11):ENSDARG00000044457 (1)

ORTHOLOGY for gfi1ab (Chr: 6)

CITATIONS (42)

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