ZFIN ID: ZDB-GENE-031219-4
Gene Name: fatty acid 2-hydroxylase
Gene Symbol: fa2h    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: cb1044 (1), zgc:153777

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 25 Mapping Details/Browsers
Description: Predicted to have fatty acid alpha-hydroxylase activity. Predicted to be involved in fatty acid metabolic process. Predicted to localize to endoplasmic reticulum. Is expressed in EVL; digestive system; ectoderm; peripheral olfactory organ; and pronephric duct. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 35. Orthologous to human FA2H (fatty acid 2-hydroxylase).
Genome Resources: Alliance (1),  Gene:792257 (1),  Ensembl(GRCz11):ENSDARG00000090063 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa8662 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fa2h HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    hereditary spastic paraplegia 35 Alliance Spastic paraplegia 35, autosomal recessive 612319
    DISEASE ASSOCIATED WITH fa2h VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fatty acid biosynthetic process (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function fatty acid alpha-hydroxylase activity (more)
    GO Terms (all 14)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fa2h-201 (1)    Ensembl 5077
    fa2h-202 (1)    Ensembl 996
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fa2h No data available
    MARKER RELATIONSHIPS
    fa2h Contained in: [BAC] CH211-172L8 (1)
    fa2h Encodes: [EST] cb1044 (1) (order this)
    [cDNA] MGC:153777 (1), MGC:191616 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045420 (1) 1027 nt
    Genomic GenBank:CR381560 (1) 145001 nt
    Select Tool
    Polypeptide UniProtKB:F1R936 (1) 377 aa
    Sequence Information (all 17)
    ORTHOLOGY for fa2h ( Chr: 25 )
    CITATIONS (21)