ZFIN ID: ZDB-GENE-031219-3
Gene Name: cytochrome P450, family 4, subfamily T, polypeptide 8
Gene Symbol: cyp4t8    Nomenclature History

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Previous Names: cyp4, cyp4a10 (1), CYP4T8 (1), cb1041 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have monooxygenase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to integral component of membrane. Is expressed in myotome; nervous system; otic vesicle; pharyngeal arch 3-7 skeleton; and somite. Human ortholog(s) of this gene implicated in hypertension. Orthologous to several human genes including CYP4B1 (cytochrome P450 family 4 subfamily B member 1).
Genome Resources: Alliance (1),  Gene:387527 (1),  Ensembl(GRCz11):ENSDARG00000004964 (1)
GENE EXPRESSION
All Expression Data: 7 figures from 3 publications
Directly Submitted Expression Data: 4 figures (12 images) from Thisse et al., 2001 [cb1041]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cyp4t8 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cyp4t8 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process oxidation-reduction process (more)
Cellular Component integral component of membrane (more)
Molecular Function heme binding (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cyp4t8-201 (1)    Ensembl 1808
cyp4t8-202 (1)    Ensembl 1811
ncRNA cyp4t8-003 (1)    Ensembl 653
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cyp4t8 No data available
MARKER RELATIONSHIPS
cyp4t8 Contained in: [BAC] CH211-256M12 (1)
cyp4t8 Encodes: [EST] cb1041 (1) (order this)
[cDNA] MGC:66042 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_199216 (1) 1906 nt
Genomic GenBank:BX927222 (1) 154714 nt
Select Tool
Polypeptide UniProtKB:E7FB64 (1) 509 aa
Sequence Information (all 13)
ORTHOLOGY for cyp4t8 ( Chr: 16 )
CITATIONS (25)