Gene

cyp4t8

ID
ZDB-GENE-031219-3
Name
cytochrome P450, family 4, subfamily T, polypeptide 8
Symbol
cyp4t8 Nomenclature History
Previous Names
  • cyp4
  • cyp4a10 (1)
  • CYP4T8 (1)
  • cb1041 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have heme binding activity; iron ion binding activity; and oxidoreductase activity. Predicted to be involved in oxidation-reduction process. Predicted to localize to integral component of membrane. Is expressed in myotome; nervous system; otic vesicle; pharyngeal arch 3-7 skeleton; and somite. Human ortholog(s) of this gene implicated in hypertension. Orthologous to several human genes including CYP4B1 (cytochrome P450 family 4 subfamily B member 1).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp4t8 Human Ortholog
No data available
Associated With cyp4t8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cytochrome P450 Cytochrome P450, conserved site Cytochrome P450, E-class, group I Cytochrome P450 superfamily
UniProtKB:E7FB64 509
UniProtKB:F1QSM0 458
UniProtKB:Q6PH32 458
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations