ZFIN ID: ZDB-GENE-031204-3 |
Gene Name: | junctional adhesion molecule 2a | ||||||
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Gene Symbol: | jam2a Nomenclature History | ||||||
Previous Names: | jam2, jamb.1 (1), jamb (1), sb:cb1002 | ||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 1 Mapping Details/Browsers | ||||||
Description: | Exhibits protein heterodimerization activity. Involved in hematopoietic or lymphoid organ development and myoblast fusion. Predicted to localize to the integral component of membrane. Is expressed in several structures, including blood vessel; musculature system; myoblast; nervous system; and pectoral fin bud. Orthologous to human JAM2 (junctional adhesion molecule 2). | ||||||
Genome Resources: | Alliance (1), Gene:100005261 (1), Ensembl(GRCz11):ENSDARG00000058996 (2) |
All Expression Data: | 13 figures from 6 publications |
Directly Submitted Expression Data: | 5 figures (11 images) from Thisse et al., 2001 [cb1002] |
Wild-type Stages, Structures: | Segmentation:1-4 somites (10.33h-11.66h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) |
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Curated Microarray Expression: | GEO (1) |
Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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hu3319 | Point Mutation | Unknown | Premature Stop | ENU | |
sa39528 | Point Mutation | Unknown | Splice Site | ENU |
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zko30a | Small Deletion | Unknown | Unknown | CRISPR |
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zko30b | Indel | Unknown | Unknown | CRISPR |
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Data: | 5 figures from 2 publications |
Observed in: |
Ontology | GO Term |
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Biological Process | myoblast fusion (more) |
Cellular Component | integral component of plasma membrane (more) |
Molecular Function | protein binding (more) |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
jam2a-201
(1)
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450 |
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jam2a-202
(1)
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707 |
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Browsers: UCSC, NCBI, Ensembl, ZFIN |
Addgene:jam2a-pCRII |
jam2a Contained in: | [BAC] CH73-41E3 (1) (order this) |
jam2a Encodes: |
[EST]
cb1002 (1) (order this)
[cDNA] cssl:d187 (1) |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:NM_001098264 (1) |
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Genomic | GenBank:CU571081 (1) | 130071 bp | |
Polypeptide | UniProtKB:A0A0R4IGV4 (1) | 307 aa |
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Sequence Clusters | UniGene:79413 (1) |