ZFIN ID: ZDB-GENE-031202-1
Gene Name: sorting nexin 8a
Gene Symbol: snx8a    Nomenclature History

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Previous Names: snx8, cb1031 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have phosphatidylinositol binding activity. Predicted to be involved in retrograde transport, endosome to Golgi. Is expressed in several structures, including EVL; periderm; tail bud; vasculature; and ventral mesoderm. Orthologous to human SNX8 (sorting nexin 8).
Genome Resources: Alliance (1),  Gene:555448 (1),  Ensembl(GRCz11):ENSDARG00000074842 (2)
GENE EXPRESSION
All Expression Data: 6 figures from 2 publications
Directly Submitted Expression Data: 5 figures (5 images) from Thisse et al., 2001 [cb1031]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa33282 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH snx8a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH snx8a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process retrograde transport, endosome to Golgi (more)
    Molecular Function phosphatidylinositol binding (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001683 Phox homologous domain
    Domain IPR035704 SNX8/Mvp1, PX domain
    Family IPR028662 Sorting nexin-8/Mvp1
    Homologous_superfamily IPR011992 EF-hand domain pair
    Homologous_superfamily IPR027267 AH/BAR domain superfamily
    Homologous_superfamily IPR036871 PX domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA snx8a-202 (1)    Ensembl 2381
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM snx8a No data available
    MARKER RELATIONSHIPS
    snx8a Contained in: [BAC] DKEY-58N10 (1) (order this), DKEY-72A22 (1) (order this)
    snx8a Encodes: [EST] cb1031 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001162443 (1)
    Genomic GenBank:BX294380 (1) 212685 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F6NGW9 (1) 519 aa
    Sequence Information (all 13)
    ORTHOLOGY for snx8a ( Chr: 3 )
    CITATIONS (17)