ZFIN ID: ZDB-GENE-031126-4
Gene Name: forkhead box I3b
Gene Symbol: foxi3b    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in epidermal cell fate specification. Predicted to localize to nucleus. Is expressed in several structures, including ectoderm; integument; ionocyte; ionocyte progenitor cell; and yolk. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 4. Orthologous to several human genes including FOXI1 (forkhead box I1).
Genome Resources: Alliance (1),  Gene:387258 (1),  Ensembl(GRCz11):ENSDARG00000009550 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22519 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-foxi3b N/A 1
    MO2-foxi3b N/A 3
    MO3-foxi3b N/A 1
    MO4-foxi3b N/A 1
    MO5-foxi3b N/A 2
    DISEASE ASSOCIATED WITH foxi3b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH foxi3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process epidermal cell fate specification (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA foxi3b-201 (1)    Ensembl 1865
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-foxi3b polyclonal Rabbit IHC 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM foxi3b No data available
    MARKER RELATIONSHIPS
    foxi3b Contained in: [BAC] CH211-232M8 (1)
    foxi3b Encodes: [cDNA] MGC:193980 (1), MGC:193987 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_198918 (1) 1300 nt
    Genomic GenBank:BX248097 (1) 171333 nt
    Select Tool
    Polypeptide UniProtKB:B3DGC2 (1) 383 aa
    Sequence Information (all 16)
    ORTHOLOGY for foxi3b ( Chr: 14 )
    CITATIONS (33)