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Gene

figla

ID
ZDB-GENE-031121-1
Name
folliculogenesis specific bHLH transcription factor
Symbol
figla Nomenclature History
Previous Names
  • fig1a (1)
  • Figa (1)
  • FIGalpha (1)
  • zgc:109752
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within female gonad development. Is expressed in gonad; ovary; and testis. Human ortholog(s) of this gene implicated in primary ovarian insufficiency 6. Orthologous to human FIGLA (folliculogenesis specific bHLH transcription factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Qin et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With figla Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ovarian insufficiency 6 Alliance Premature ovarian failure 6 612310
Associated With figla Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain
UniProtKB:Q6W9E1 220
UniProtKB:Q568W8 220
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations