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ZIRC
ZFIN ID: ZDB-GENE-031121-1
Gene Name: folliculogenesis specific bHLH transcription factor
Gene Symbol: figla
Sequence Ontology ID : SO:0001217

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Previous Names: fig1a (1), Figa (1), FIGalpha (1), zgc:109752

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have protein dimerization activity. Involved in female gonad development. Human ortholog(s) of this gene implicated in premature ovarian failure. Is expressed in gonad. Orthologous to  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:109752]
Wild-type Stages, Structures: Larval:Days 21-29 (21d-30d, 7.8mm, 10 teeth) to Adult (90d-730d, breeding adult)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
umo14 Indel Unknown Unknown CRISPR
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH figla HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
premature ovarian failure Premature ovarian failure 6 612310
DISEASE ASSOCIATED WITH figla VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process female gonad development (more)
Molecular Function protein dimerization activity (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR011598 (1)
  • InterPro:IPR036638 (1)
  • PROSITE:PS50888 (1)
  • Pfam:PF00010 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA figla-201 (1) 1122
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM figla No data available
    MARKER RELATIONSHIPS
    figla Contained in: [BAC] CH73-367H4 (1) (order this)
    figla Encodes: [cDNA] MGC:109752 (1) (order this), MGC:191492 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_198919 (1) 1140 bp
    Genomic GenBank:CU896567 (1) 116731 bp
    Select Tool
    Polypeptide UniProtKB:Q568W8 (1) 220 aa
    Sequence Clusters UniGene:29104 (1)
    Sequence Information (all 18)
    ORTHOLOGY for figla ( Chr: 5 )
    CITATIONS (24)