ZFIN ID: ZDB-GENE-031113-6
Gene Name: poly (ADP-ribose) polymerase 2
Gene Symbol: parp2    Nomenclature History

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Previous Names: adprtl2 (1), cb996 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have NAD+ ADP-ribosyltransferase activity and protein ADP-ribosylase activity. Predicted to be involved in double-strand break repair and protein poly-ADP-ribosylation. Predicted to localize to nucleolus. Is expressed in brain; head; and proliferative region. Orthologous to human PARP2 (poly(ADP-ribose) polymerase 2).
Genome Resources: Alliance (1),  Gene:100007906 (1),  Ensembl(GRCz11):ENSDARG00000079202 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023665Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la023666Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6855 Point Mutation Unknown Premature Stop ENU
    sa9953 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14277 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31291 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-parp2 N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH parp2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH parp2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein ADP-ribosylation (more)
    Cellular Component nucleolus (more)
    Molecular Function NAD+ ADP-ribosyltransferase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA parp2-202 (1)    Ensembl 813
    parp2-203 (1)    Ensembl 2629
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM parp2 No data available
    MARKER RELATIONSHIPS
    parp2 Contained in: [BAC] CH211-284O19 (1)
    parp2 Encodes: [EST] cb996 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001204270 (1)
    Genomic GenBank:AL954692 (1) 101677 nt
    Select Tool
    Polypeptide UniProtKB:F1QLV3 (1) 649 aa
    Sequence Information (all 17)
    ORTHOLOGY for parp2 ( Chr: 2 )
    CITATIONS (27)