Gene

tardbpl

ID
ZDB-GENE-031030-1
Name
TAR DNA binding protein, like
Symbol
tardbpl Nomenclature History
Previous Names
  • tardbp
  • wu:fb52e05
  • wu:fe47c11
  • wu:fj94b04
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have RNA binding activity. Involved in several processes, including axon extension; neuromuscular junction development; and skeletal muscle tissue development. Predicted to localize to nuclear chromatin and nucleoplasm. Is expressed in brain and fin. Human ortholog(s) of this gene implicated in Parkinson's disease; amyotrophic lateral sclerosis; amyotrophic lateral sclerosis type 10; and motor neuron disease. Orthologous to several human genes including TARDBP (TAR DNA binding protein).
Genome Resources
Note
None
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tardbpl Human Ortholog
No data available
Associated With tardbpl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR041105 TAR DNA-binding protein 43, N-terminal
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain TAR DNA-binding protein 43, N-terminal
UniProtKB:A0A2R8PYV5 304
UniProtKB:Q803N5 303
UniProtKB:Q6NYX2 298
UniProtKB:A0A2R8QEL5 402
UniProtKB:X1WD19 401
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-tardbpl monoclonal IgG2a Rat
  • WB
1
Ab2-tardbpl monoclonal IgG2c Rat
1
Ab3-tardbpl monoclonal IgG2a Rat
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations