ZFIN ID: ZDB-GENE-031016-1
Gene Name: inhibitor of growth family, member 5a
Gene Symbol: ing5a    Nomenclature History

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Previous Name: ing5

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have chromatin binding activity and methylated histone binding activity. Predicted to be involved in negative regulation of cell population proliferation; positive regulation of apoptotic signaling pathway; and positive regulation of transcription, DNA-templated. Predicted to localize to the nucleus. Orthologous to human ING5 (inhibitor of growth family member 5).
Genome Resources: Alliance (1),  Gene:792168 (1),  Ensembl(GRCz11):ENSDARG00000022413 (2)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1695 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ing5a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ing5a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ing5a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chromatin organization (more)
    Cellular Component MOZ/MORF histone acetyltransferase complex (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR001965 Zinc finger, PHD-type
    Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
    Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
    Conserved_site IPR019786 Zinc finger, PHD-type, conserved site
    Domain IPR019787 Zinc finger, PHD-finger
    Domain IPR024610 Inhibitor of growth protein, N-terminal histone-binding
    Family IPR028638 Inhibitor of growth protein 5
    Family IPR028651 ING family
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ing5a-201 (1)    Ensembl 1054
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ing5a No data available
    MARKER RELATIONSHIPS
    ing5a Contained in: [BAC] CH73-159L23 (1)
    ing5a Encodes: [cDNA] MGC:194002 (1), MGC:194029 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001100049 (1)
    Genomic GenBank:CT027565 (1) 79954 bp
    Select Tool
    Polypeptide UniProtKB:A5WVS7 (1) 242 aa
    Sequence Information (all 16)
    ORTHOLOGY for ing5a ( Chr: 22 )
    CITATIONS (24)