Gene

ttc21b

ID
ZDB-GENE-031010-34
Name
tetratricopeptide repeat domain 21B
Symbol
ttc21b Nomenclature History
Previous Names
  • sb:cb947
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Involved in gastrulation. Predicted to localize to intraciliary transport particle A. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy 4 and nephronophthisis 12. Is expressed in Kupffer's vesicle; forerunner cell group; neural tube; and pronephric duct. Orthologous to human TTC21B (tetratricopeptide repeat domain 21B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Davis et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ttc21b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
asphyxiating thoracic dystrophy 4 Alliance Short-rib thoracic dysplasia 4 with or without polydactyly 613819
nephronophthisis 12 Alliance Nephronophthisis 12 613820
Associated With ttc21b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR040364 Tetratricopeptide repeat protein 21A/21B
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Repeat IPR019734 Tetratricopeptide repeat
Domain Details Per Protein
Protein Length Tetratricopeptide-like helical domain superfamily Tetratricopeptide repeat Tetratricopeptide repeat protein 21A/21B
UniProtKB:B0R0W1 1321
UniProtKB:A0A0J9YJ68 188
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations