ZFIN ID: ZDB-GENE-031010-21
Gene Name: fibrinogen alpha chain
Gene Symbol: fga
Previous Names: sb:cb892, wu:fa55c12, wu:fb20e08, wu:fb59b03, wu:fi39d04, zgc:92117
Location: Chr: 1 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 5 publications
Directly Submitted Expression Data: 5 figures (5 images) from Thisse et al., 2001 [cb892]
Wild-type Stages, Structures: Segmentation:10-13 somites (14.0h-16.0h) to Adult (90d-730d, breeding adult)
  liver, whole organism, YSL
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
sa12469 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-fga (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fga HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    congenital afibrinogenemia Afibrinogenemia, congenital 202400
    familial visceral amyloidosis Amyloidosis, familial visceral 105200
    Dysfibrinogenemia, congenital 616004
    Hypodysfibrinogenemia, congenital 616004
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood coagulation, fibrin clot formation (more)
    Cellular Component fibrinogen complex (more)
    Molecular Function protein binding, bridging (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002181 (1)
  • InterPro:IPR012290 (1)
  • InterPro:IPR014715 (1)
  • InterPro:IPR014716 (1)
  • InterPro:IPR020837 (1)
  • PROSITE:PS00514 (1)
  • PROSITE:PS51406 (1)
  • Pfam:PF00147 (1)
  • Pfam:PF08702 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fga-001 (1) 2366
    fga-002 (1) 2469
    ncRNA fga-003 (1) 690
    fga-004 (1) 768
    fga-005 (1) 751
    fga-006 (1) 503
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fga No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    fgaContained in: [BAC] DKEYP-75B4 (1)
    fgaEncodes: [EST] cb892 (1) (order this), fa55c12, fb20e08, fb59b03, fi39d04
    [cDNA] MGC:92117 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001194989 (1) 2349bp
    Genomic GenBank:BX548256 (1) 181272bp
    Select Tool
    Polypeptide UniProtKB:B8A5L6 (1) 684aa
    Sequence Clusters UniGene:33271 (1)
    Sequence Information (all 23)
    OTHER fga GENE PAGES
  • Gene:378986 (1)
  • VEGA:OTTDARG00000019537 (1)
  • Ensembl(GRCz10):ENSDARG00000020741 (1)
  • ORTHOLOGY for fga (Chr: 1)
    Species Symbol Chromosome Accession # Evidence
    Human FGA 4
  • Gene:2243
  • OMIM:134820
  • HGNC:3661
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Fga 3
  • MGI:1316726
  • Gene:14161
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (22)