Gene

lhx8a

ID
ZDB-GENE-031008-2
Name
LIM homeobox 8a
Symbol
lhx8a Nomenclature History
Previous Names
  • lhx7 (1)
  • lhx8
  • cb875 (1)
  • fk78g12 (1)
  • wu:fk78g12 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in forebrain neuron development and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be active in nucleus. Is expressed in brain; dental mesenchyme; and pharynx. Orthologous to human LHX8 (LIM homeobox 8).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lhx8a Human Ortholog
No data available
Associated With lhx8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Domain IPR001781 Zinc finger, LIM-type
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Zinc finger, LIM-type
UniProtKB:F6NIJ6 237
UniProtKB:A5PMV8 332
UniProtKB:Q6BDC3 332
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations