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ZIRC
ZFIN ID: ZDB-GENE-031006-6
Gene Name: neutrophil cytosolic factor 1
Gene Symbol: ncf1
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: cb893 (1), p47phox (1)

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have phosphatidylinositol binding activity and superoxide-generating NADPH oxidase activator activity; involved in defense response to fungus and respiratory burst; predicted to localize  ...
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (3 images) from Thisse et al., 2001 [cb893]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31481 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33742 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 2 figures from Brothers et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH ncf1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal recessive chronic granulomatous disease cytochrome b-positive type I Chronic granulomatous disease due to deficiency of NCF-1 233700
    DISEASE ASSOCIATED WITH ncf1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process defense response to fungus (more)
    Cellular Component cytoplasm (more)
    Molecular Function phosphatidylinositol binding (more)
    GO Terms (all 10)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ncf1-201 (1) 2133
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ncf1 No data available
    MARKER RELATIONSHIPS
    ncf1Contained in: [BAC] DKEYP-36F5 (1)
    ncf1Encodes: [EST] cb893 (1) (order this), fm62b10 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030071 (1) 2165bp
    Genomic GenBank:BX294180 (1) 69889bp
    Select Tool
    Polypeptide UniProtKB:A2BFP2 (1) 410aa
    Sequence Clusters UniGene:2973 (1)
    Sequence Information (all 13)
    ORTHOLOGY for ncf1 (Chr: 5)
    CITATIONS (37)