ZFIN ID: ZDB-GENE-031006-4
Gene Name: 4-aminobutyrate aminotransferase
Gene Symbol: abat    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: GABA-T (1), cb880 (1), fj82a01, wu:fj82a01 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Predicted to have 4-aminobutyrate transaminase activity and pyridoxal phosphate binding activity. Predicted to be involved in gamma-aminobutyric acid catabolic process. Predicted to localize to mitochondrion. Is expressed in blood; liver; nervous system; pronephric duct; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Alzheimer's disease; GABA aminotransferase deficiency; and Huntington's disease. Orthologous to human ABAT (4-aminobutyrate aminotransferase).
Genome Resources: Alliance (1),  Gene:378968 (1),  Ensembl(GRCz11):ENSDARG00000006031 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028889Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38392 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abat HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    GABA aminotransferase deficiency Alliance GABA-transaminase deficiency 613163
    DISEASE ASSOCIATED WITH abat VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process gamma-aminobutyric acid metabolic process (more)
    Cellular Component mitochondrion (more)
    Molecular Function 4-aminobutyrate transaminase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA abat-202 (1)    Ensembl 2179
    ncRNA abat-002 (1)    Ensembl 666
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM abat No data available
    MARKER RELATIONSHIPS
    abat Contained in: [BAC] CH73-86A17 (1)
    abat Encodes: [EST] cb880 (1) (order this), fj82a01
    [cDNA] MGC:55707 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201498 (1) 2253 nt
    Genomic GenBank:CU464204 (1) 93246 nt
    Select Tool
    Polypeptide UniProtKB:I3IRW7 (1) 500 aa
    Sequence Information (all 13)
    ORTHOLOGY for abat ( Chr: 3 )
    CITATIONS (36)