Gene

rgs12b

ID

ZDB-GENE-031006-13

Name

regulator of G protein signaling 12b

Symbol

rgs12b Nomenclature History

Previous Names

rgs12 (1)
cb958 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have GTPase regulator activity. Predicted to be involved in signal transduction. Is expressed in retina and ventricular zone. Orthologous to human RGS12 (regulator of G protein signaling 12).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from Thisse et al., 2001

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb958 (4 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With rgs12b Human Ortholog

No data available

Associated With rgs12b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR003109	GoLoco motif
Domain	IPR001478	PDZ domain
Domain	IPR003116	Raf-like Ras-binding
Domain	IPR006020	PTB/PI domain
Domain	IPR016137	RGS domain
Domain	IPR037880	RGS12, RGS domain
Family	IPR046995	Regulator of G-protein signaling 10/12/14-like
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR024066	RGS, subdomain 1/3
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR036034	PDZ superfamily
Homologous_superfamily	IPR036305	RGS domain superfamily
Homologous_superfamily	IPR044926	RGS, subdomain 2

Domain Details Per Protein

Protein	Length	GoLoco motif	PDZ domain	PDZ superfamily	PH-like domain superfamily	PTB/PI domain	Raf-like Ras-binding	Regulator of G-protein signaling 10/12/14-like	RGS12, RGS domain	RGS domain	RGS domain superfamily	RGS, subdomain 1/3	RGS, subdomain 2	Ubiquitin-like domain superfamily
UniProtKB:A0A8M3AU63 InterPro	727
UniProtKB:A0A8M3B2C1 InterPro	713
UniProtKB:Q6T9C1 InterPro	1183
UniProtKB:Q6T9C2 InterPro	1387
UniProtKB:Q6T9C3 InterPro	1540

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	rgs12b-201 (1) Ensembl	Ensembl	5,981 nt	Select Tool
mRNA	rgs12b-202 (1) Ensembl	Ensembl	5,413 nt	Select Tool
mRNA	rgs12b-203 (1) Ensembl	Ensembl	5,510 nt	Select Tool
ncRNA	rgs12b-004 (1) Ensembl	Ensembl	625 nt	Select Tool
ncRNA	rgs12b-005 (1) Ensembl	Ensembl	310 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations