Gene
rgs12b
- ID
- ZDB-GENE-031006-13
- Name
- regulator of G protein signaling 12b
- Symbol
- rgs12b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to enable GTPase activator activity. Predicted to be involved in regulation of G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Is expressed in retina and ventricular zone. Orthologous to human RGS12 (regulator of G protein signaling 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Thisse et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb958 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR003109 | GoLoco motif |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR003116 | Raf-like Ras-binding |
| Domain | IPR006020 | PTB/PI domain |
| Domain | IPR016137 | RGS domain |
| Domain | IPR037880 | RGS12, RGS domain |
| Family | IPR046995 | Regulator of G-protein signaling 10/12/14-like |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR024066 | RGS, subdomain 1/3 |
| Homologous_superfamily | IPR029071 | Ubiquitin-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
| Homologous_superfamily | IPR036305 | RGS domain superfamily |
| Homologous_superfamily | IPR044926 | RGS, subdomain 2 |
Domain Details Per Protein
| Protein | Additional Resources | Length | GoLoco motif | PDZ domain | PDZ superfamily | PH-like domain superfamily | PTB/PI domain | Raf-like Ras-binding | Regulator of G-protein signaling 10/12/14-like | RGS12, RGS domain | RGS domain | RGS domain superfamily | RGS, subdomain 1/3 | RGS, subdomain 2 | Ubiquitin-like domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3AU63 | InterPro | 727 | |||||||||||||
| UniProtKB:A0A8M3B2C1 | InterPro | 713 | |||||||||||||
| UniProtKB:Q6T9C1 | InterPro | 1183 | |||||||||||||
| UniProtKB:Q6T9C2 | InterPro | 1387 | |||||||||||||
| UniProtKB:Q6T9C3 | InterPro | 1540 | |||||||||||||
| UniProtKB:A0AB32T0B4 | InterPro | 1143 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rgs12b-201
(1)
|
Ensembl | 5,981 nt | ||
| mRNA |
rgs12b-202
(1)
|
Ensembl | 5,413 nt | ||
| mRNA |
rgs12b-203
(1)
|
Ensembl | 5,510 nt | ||
| ncRNA |
rgs12b-004
(1)
|
Ensembl | 625 nt | ||
| ncRNA |
rgs12b-005
(1)
|
Ensembl | 310 nt |
Interactions and Pathways
No data available
Plasmids
No data available