ZFIN ID: ZDB-GENE-031006-12
Gene Name: ATP-binding cassette, sub-family A (ABC1), member 1A
Gene Symbol: abca1a
Sequence Ontology ID : SO:0000704

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Previous Names: abca1, cb939 (1), fa03d03, im:6795541, wu:fa03d03, wu:fj13h01

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Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (15 images) from Thisse et al., 2001 [cb939]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
  artery, basal plate midbrain region, central nervous system, diencephalon (all 18) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa928 Point Mutation Unknown Splice Site ENU
sa2010 Point Mutation Unknown Splice Site ENU
sa5800 Point Mutation Unknown Splice Site ENU
sa9624 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12376 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13007 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa15548 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa32775 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39699 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: MO1-abca1a (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH abca1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    familial hypercholesterolemia {Coronary artery disease in familial hypercholesterolemia, protection against} 143890
    Tangier disease Tangier disease 205400
    HDL deficiency, type 2 604091
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of cholesterol efflux (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003439
  • InterPro:IPR003593
  • InterPro:IPR017871
  • InterPro:IPR026082
  • InterPro:IPR027417
  • PROSITE:PS00211
  • PROSITE:PS50893
  • Pfam:PF00005
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA abca1a-001 (1) 9428
    ncRNA abca1a-002 (1) 697
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM abca1a No data available
    MARKER RELATIONSHIPS
    abca1aContained in: [BAC] CH211-149G8 (1) (order this)
    abca1aEncodes: [EST] cb939 (1) (order this), fa03d03, fj13h01, IMAGE:6795541
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001309465 (1) 9626bp
    Genomic GenBank:BX004781 (1) 169991bp
    Select Tool
    Polypeptide UniProtKB:B8A446 2268aa
    Sequence Clusters UniGene:122299 (1)
    Sequence Information (all 17)
    OTHER abca1a GENE PAGES
  • Gene:558924 (1)
  • VEGA:OTTDARG00000029861 (1)
  • Ensembl(GRCz10):ENSDARG00000074635 (1)
  • ORTHOLOGY for abca1a (Chr: 1)
    CITATIONS (20)