ZFIN ID: ZDB-GENE-031001-6
Gene Name: SH3-domain GRB2-like 1b
Gene Symbol: sh3gl1b    Nomenclature History

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Previous Names: cb831 (1), sh3gl1 (1), eena (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to localize to cytoplasm. Is expressed in several structures, including cardiovascular system; mesoderm; musculature system; nervous system; and neural tube. Human ortholog(s) of this gene implicated in acute myeloid leukemia and malignant glioma. Orthologous to human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2).
Genome Resources: Alliance (1),  Gene:378838 (1),  Ensembl(GRCz11):ENSDARG00000002642 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa2439 Point Mutation Unknown Splice Site ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-sh3gl1b N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH sh3gl1b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
acute myeloid leukemia Alliance Leukemia, acute myeloid 601626
DISEASE ASSOCIATED WITH sh3gl1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component cytoplasm (more)
GO Terms (all 1)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA sh3gl1b-201 (1)    Ensembl 1776
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM sh3gl1b No data available
MARKER RELATIONSHIPS
sh3gl1b Contained in: [BAC] DKEY-192C10 (1) (order this)
sh3gl1b Encodes: [EST] cb831 (1) (order this)
[cDNA] MGC:56143 (1), MGC:191342 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_201497 (1) 1662 nt
Genomic GenBank:CR450766 (1) 132667 nt
Select Tool
Polypeptide UniProtKB:A0A2R8QNY2 (1) 368 aa
Sequence Information (all 24)
ORTHOLOGY for sh3gl1b ( Chr: 8 )
CITATIONS (21)